17115-51-4

Basic information

• Product Name: 1,1-DIOXO-TETRAHYDRO-1LAMBDA*6*-THIOPHEN-3-ONE
• Synonyms: 1,1-DIOXO-TETRAHYDRO-1LAMBDA*6*-THIOPHEN-3-ONE;DIHYDROTHIOPHEN-3(2H)-ONE 1,1-DIOXIDE;Tetrahydrothiophene-3-oxo-1,1-dioxide;dihydrothiophen-3(2H)-one 1,1-dioxide(SALTDATA: FREE);3(2H)-Thiophenone, dihydro-, 1,1-dioxide;Dihydro-3(2H)-thiophenone 1,1-dioxide;1,1-diketo-2,3-dihydrothiophen-3-ol;3-Hydroxy-2,3-dihydrothiophene 1,1-dioxide
• CAS NO: 17115-51-4
• Molecular Formula: C₄H₆O₃S
• Molecular Weight: 134.15
• Mol File: 17115-51-4.mol
• Article Data: 11

Chemical Properties

• Melting Point: 62 °C(Solv: ethanol (64-17-5))
• Boiling Point: 393.3 °C at 760 mmHg
• Flash Point: 282.7 °C
• Appearance: /
• Density: 1.461 g/cm³
• Vapor Pressure: 2.15E-06mmHg at 25°C
• Refractive Index: 1.51
• CAS DataBase Reference: 1,1-DIOXO-TETRAHYDRO-1LAMBDA*6*-THIOPHEN-3-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-DIOXO-TETRAHYDRO-1LAMBDA*6*-THIOPHEN-3-ONE(17115-51-4)
• EPA Substance Registry System: 1,1-DIOXO-TETRAHYDRO-1LAMBDA*6*-THIOPHEN-3-ONE(17115-51-4)

Safety Data

• Hazardous Substances Data: 17115-51-4(Hazardous Substances Data)

Usage

General Description

1,1-Dioxo-tetrahydro-1lambda*6*-thiophen-3-one is a chemical compound that belongs to the class of thiophenes. It is a cyclic sulfide with a dioxo functional group and a tetrahydro-thiophen ring. 1,1-DIOXO-TETRAHYDRO-1LAMBDA*6*-THIOPHEN-3-ONE is used in the production of organic chemicals, pharmaceuticals, and agrochemicals. It may also have potential applications in the field of materials science as a building block for the synthesis of novel organic compounds. Additionally, it is utilized in research and development for its unique chemical and structural properties.

InChI:InChI=1/C4H6O3S/c5-4-1-2-8(6,7)3-4/h1-3H2

Upstream product

• 7311-83-3 3,3-dimethoxy-tetrahydrothiophene 1,1-dioxide 
• 13031-76-0 3-hydroxytetrahydrothiophene-1,1-dioxide 
• 82813-84-1 3-benzyloxy-4,5-dihydrothiophene-1,1-dioxide 
• 20688-40-8 trans-3-bromo-4-dihydroxythiolane 1,1-dioxide 
• 82813-57-8 3-octylthio-4,5-dihydrothiophene-1,1-dioxide 
• 82813-65-8 3-pentylthio-4,5-dihydrothiophene-1,1-dioxide 
• 82813-49-8 3-Octylsulfanyl-2,5-dihydro-thiophene 1,1-dioxide 
• 82813-47-6 3-Pentylsulfanyl-2,5-dihydro-thiophene 1,1-dioxide 

Downstream Products

• 927672-12-6 7-(3-bromo-4-fluoro-phenyl)-5-ethyl-1,1-dioxo-2,3,4,7-tetrahydro-1H-1λ⁶-thieno[3,2-b]pyridine-6-carboxylic acid methyl ester 
• 1338580-06-5 5-amino-2,3,4,7-tetrahydro-7-(3-bromophenyl)-1,1-dioxothieno[3,2-b]pyran-6-carbonitrile 
• 1338580-05-4 5-amino-2,3,4,7-tetrahydro-7-(4-methylphenyl)-1,1-dioxothieno[3,2-b]pyran-6-carbonitrile 
• 1338579-99-9 5-amino-2,3,4,7-tetrahydro-7-(4-fluorophenyl)-1,1-dioxothieno[3,2-b]pyran-6-carbonitrile 
• 1338580-01-0 5-amino-2,3,4,7-tetrahydro-7-(4-chlorophenyl)-1,1-dioxothieno[3,2-b]pyran-6-carbonitrile 
• 1338580-00-9 5-amino-2,3,4,7-tetrahydro-7-(2-chlorophenyl)-1,1-dioxothieno[3,2-b]pyran-6-carbonitrile 
• 1338580-15-6 ethyl 5-amino-2,3,4,7-tetrahydro-7-(3-nitrophenyl)-1,1-dioxothieno[3,2-b]pyran-6-carboxylate 
• 1338580-07-6 5-amino-2,3,4,7-tetrahydro-7-(4-nitrophenyl)-1,1-dioxothieno[3,2-b]pyran-6-carbonitrile 
• 1338580-04-3 5-amino-2,3,4,7-tetrahydro-7-(3,4,5-trimethoxyphenyl)-1,1-dioxothieno[3,2-b]pyran-6-carbonitrile 
• 1338579-96-6 5-amino-2,3,4,7-tetrahydro-7-phenyl-1,1-dioxothieno[3,2-b]pyran-6-carbonitrile 
• 1338580-02-1 5-amino-2,3,4,7-tetrahydro-7-(4-methoxyphenyl)-1,1-dioxothieno[3,2-b]pyran-6-carbonitrile 
• 1338580-13-4 ethyl 5-amino-2,3,4,7-tetrahydro-7-(2,4-dichlorophenyl)-1,1-dioxothieno[3,2-b]pyran-6-carboxylate 
• 1338580-08-7 5-amino-2,3,4,7-tetrahydro-7-(2,4-dichlorophenyl)-1,1-dioxothieno[3,2-b]pyran-6-carbonitrile 
• 1338580-16-7 ethyl 5-amino-2,3,4,7-tetrahydro-7-(3-chlorophenyl)-1,1-dioxothieno[3,2-b]pyran-6-carboxylate 

Relevant articles and documents

A Convenient Multigram Scale Synthesis of Tetrahydrothiophene-3-one-1,1-dioxide

A short and efficient multigram scale synthesis of tetrahydrothiophene-3-one-1,1-dioxide is described.

IMIDAZO [4, 5 -C] PYRIDINE DERIVATIVES USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES

Wherein R1, L1, R3, R4, Cy, L2 and R5 are as defined herein. Novel imidazolopyridines according to Formula I, able to inhibit JAK are disclosed, these compounds may be prepared as a pharmaceutical composition, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, allergic or inflammatory conditions, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 or interferons.

Synthesis and myorelaxant activity of fused 1,4-dihydropyridines on isolated rabbit gastric fundus

Strategy, Management and Health Policy Preclinical Research In the present study, 25 novel condensed 1,4-dihydropyridine (DHP) derivatives bearing cyclopentane, cyclohexane, or tetrahydrothiopene ring with a bulky and lipophilic moiety (3-pyridylmethyl) in the ester group were synthesized via a modified Hantzsch reaction, and their calcium channel modulator activities were assayed on isolated rabbit gastric fundus smooth muscle strips. To evaluate the myorelaxant effects of the compounds, the maximum relaxant response (Emax) and pD 2 values were calculated. The results indicated that all compounds produced concentration-dependent relaxation and the introduction of five- or six-membered rings to the DHP nucleus and 3-pyridiylmethyl moiety to the ester group led to potent calcium antagonists.