171232-23-8Relevant articles and documents
Fluorinated substrates result in variable leakage of a reaction intermediate during catalysis by dehydroquinate synthase
Negron, Leonardo,Parker, Emily J
, p. 2861 - 2867 (2011)
Incubation of (3S)-3-fluoro-3-deoxy-d-arabino-heptulosonate 7-phosphate with dehydroquinate (DHQ) synthase from three phylogenetically distinct sources resulted in the production of (6S)-6-fluoroDHQ and its epimer 1-epi-(6S)-6-fluoroDHQ. The differences i