171272-37-0

Upstream product

• 110544-98-4 (2S)-5-benzyloxycarbonyl-2-(tert-butoxycarbonyl)aminopentanoic acid dicyclohexylammonium salt 
• 171272-35-8 (S)-3-hydroxy-15-methylhexadecanamide 
• 2485-71-4 13-methyltetradecanoic acid 
• 83549-87-5 13-methyltetradecanoic acid chloride 
• 171272-08-5 WA₈₂₄₂B 
• 213336-71-1 (3S)-3-[(2S)-5-benzyloxycarbonyl-2-{(3S)-3-hydroxy-15-methylhexadecanoyl}aminopentanoyl]oxy-15-methylhexadecanamide 
• 112295-37-1 δ-benzyl N-(tert-butyloxycarbonyl)-DL-aminoadipate 
• 56602-33-6 (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate 
• 213197-32-1 methyl (S)-3-hydroxy-15-methylhexadecanoate 
• 213197-34-3 methyl 15-methyl-3-oxo-hexadecanoate 
• 171272-36-9 (3S)-3-hydroxy-15-methylhexadecanoic acid 

Downstream Products

• 213336-71-1 (3S)-3-[(2S)-5-benzyloxycarbonyl-2-{(3S)-3-hydroxy-15-methylhexadecanoyl}aminopentanoyl]oxy-15-methylhexadecanamide 
• 213197-35-4 (S)-2-Amino-hexanedioic acid 6-benzyl ester 1-((S)-1-carbamoylmethyl-13-methyl-tetradecyl) ester 

Relevant academic research and scientific papers

Amino acid derivatives and their use as phospholipase A2 inhibitor

PCT No. PCT/JP95/00068 Sec. 371 Date Nov. 12, 1996 Sec. 102(e) Date Nov. 12, 1996 PCT Filed Jan. 23, 1995 PCT Pub. No. WO95/19959 PCT Pub. Date Jul. 27, 1995The present invention relates to a novel fatty acid derivative of the following formula: wherein R

WA8242A1, A2 and B, novel secretary phospholipase A2 inhibitors produced by Streptomyces violaceusniger. III. Structure elucidation and total synthesis of WA8242B

The structure of WA8242B, a potent novel inhibitor against phospholipase A2, was fully characterized by spectroscopic methods and chemical degradation. The success of total synthesis of WA8242B confirmed the structure and allowed the pharmacological study of WA8242B. The structures of WA8242A1 and A2 were also described.