171494-08-9Relevant academic research and scientific papers
METHOD, COMPOSITIONS, AND COMPOUNDS FOR ALLOSTERIC MODULATION OF THE GABA RECEPTOR BY MEMBERS OF THE ANDROSTANE AND PREGNANE SERIES
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, (2008/06/13)
Methods, compositions, and compounds for modulating the GABA. sub.A receptor-chloride ionophore complex to alleviate stress, anxiety, seizures, mood disorders, PMS and PND and to induce anesthesia.
3α-Hydroxy-3β-(phenylethynyl)-5β-pregnan-20-ones: Synthesis and pharmacological activity of neuroactive steroids with high affinity for GABA(A) receptors
Upasani, Ravindra B.,Yang, Kevin C.,Acosta-Burruel, Manuel,Konkoy, Chris S.,McLellan, James A.,Woodward, Richard M.,Lan, Nancy C.,Carter, Richard B.,Hawkinson, Jon E.
, p. 73 - 84 (2007/10/03)
Neuroactive steroids that allosterically modulate GABA(A) receptors have potential uses as anticonvulsants, anxiolytics, and sedative-hypnotic agents. Recently, a series of pregnanes substituted with simple alkyl groups at the 3β-position were synthesized
