171516-53-3Relevant academic research and scientific papers
Synthesis and antihyperglycemic evaluation of various protoberberine derivatives
Bian, Xiaoli,He, Langchong,Yang, Guangde
, p. 1380 - 1383 (2007/10/03)
Various berberine derivatives (2-17) were synthesized and their antihyperglycemic activities were evaluated in a model of β-cell-membrane chromatography and a model of alloxan-induced diabetes mice. The results indicated that compounds 5 and 14 exhibited antihyperglycemic activity. Their structure-activity relationships were discussed.
SYNTHESES BASED ON &β-PHENYLETHYLAMINES V. SYNTHESIS AND PRELIMINARY PHARMACOLOGICAL SCREENING OF SOME PHENYLALKYLAMINES AND N-BENZYLTETRAHYDROISOQUINOLINES
Vinogradova, V. I.,Golodnyuk, T. I.,Yunusov, M. S.,Suleimanova, G. A.,Tulyaganov, N.
, p. 654 - 657 (2007/10/02)
The synthetic series of substituted N-benzyltetrahydroisoquinolines has been continued and the pharmacological activities of the compounds obtained have been investigated.
