171523-66-3Relevant academic research and scientific papers
Chiral sulfoxides in asymmetric synthesis: Enantioselective synthesis of the lactonic moiety of (+)-compactin and (+)-mevinolin. Application to a compactin analogue
Solladie,Bauder,Rossi
, p. 7774 - 7777 (1995)
The lactonic part of (+)-compactin and (+)-mevinolin as well as a compactin analogue were synthesized in an enantioselective way from a β,δ-diketo sulfoxide easily obtained by the reaction of the trianion of methyl 3,5-dioxohexanoate with (-)-menthyl (S)-p-toluenesulfinate. The main reaction was the two-step stereoselective reduction of β,δ-diketo sulfoxide without any protective group.
Enantioselective synthesis of a bicyclic ketal induced by chiral sulfoxides: (-)-(1R,3R,5S)-endo-1,3-dimethyl-2,9-dioxabicyclo-[3,3,1]-nonane
Solladie,Huser
, p. 2679 - 2682 (2007/10/03)
The bicyclic ketal, (-)-(1R,3R,5S)-1,3-dimethyl-2,9-dioxabicyclo-[3,3,1]-nonane, was prepared by a short enantioselective reduction of an enantiomerically pure β,δ-diketosulfoxide.
