171561-65-2Relevant academic research and scientific papers
A general synthesis of enantiopure 1,2-aminoalcohols via chiral morpholinones
Segat-Dioury, Fabienne,Lingibé, Olivier,Graffe, Bernadette,Sacquet, Marie-Claude,Lhommet, Gérard
, p. 233 - 248 (2007/10/03)
Eleven optically active 1,2-aminoalcohols 20a-i and 26b-c were prepared from D-phenylglycine via cyclic imines 7b-i (or enamine 7a). The key step of the strategy is the diastereoselective reduction of chiral oxazinones 7a-i.
Asymmetric Synthesis with Chiral Hydrogenolysable Amines: A New Route to Enantiopure Cyclic β-Amino Alcohols
Lingibe, Olivier,Graffe, Bernadette,Sacquet, Marie-Claude,Lhommet, Gerard
, p. 1931 - 1934 (2007/10/02)
Enantiopure prolinol and pipecolinol have been obtained via diastereoselective chemical reduction of chiral 2,3-dihydro-6H-1,4-oxazin-2-ones (5).
