171612-69-4

Upstream product

• 171612-62-7 Carbonic acid allyl ester (2R,3R,4R,5R)-5-(6-allyloxycarbonylamino-purin-9-yl)-4-allyloxycarbonyloxy-2-hydroxymethyl-tetrahydro-furan-3-yl ester 
• 171612-60-5 N⁶-<(allyloxy)carbonyl>-3'-O-(tert-butyldimethylsilyl)-5'-O-(p-methoxytrityl)-adenosine 

Relevant academic research and scientific papers

Preparation of short oligonucleotides via the phosphoramidite method using a tetrazole promoter in a catalytic manner

A facile phosphoramidite method using a tetrazole promoter in a catalytic manner has been developed for the condensation of a nucleoside 3'-phosphoramidite and a nucleoside. This method is particularly useful for a large-scale synthesis of short oligonucl

Regiodefined synthesis and conformational properties of adenyldiyl trimers with unsymmetrical 2'-5' and 3'-5' internucleotide linkages

Adenyldiyl trimers with different kinds of substituents on 2'-5' and 3'-5' phosphate linkages have been synthesized in a general, regiodefined manner. Examination of the 2D NMR spectra reveals that the trimers with adenyl(2'-5')adenosine linkage make a syn-anti as well as syn-syn base stack between the two adenyl bases and exist as a mixture of the two conformers.