171775-51-2Relevant academic research and scientific papers
Synthesis of fluorovinylsalicylic acids and their derivatives
Filler, Robert,Lin, Shan,Zhang, Zhaoxu
, p. 69 - 76 (1995)
Palladium-catalyzed cross-coupling of iodosalicylic acid derivatives with polyfluorovinyl zinc reagents provided the corresponding fluorovinyl-substituted salicylates.Methyl-5-(β,β)-difluorovinyl methyl salicylate was prepared by a Wittig reaction of the 5-formyl compound with the strongly nucleophilic ylide, .In one sequence, a fluorine-free benzofuran was obtained, instead of a difluorovinylsalicylate. - Keywords: Fluorovinylsalicylic acids; Wittig reaction; Benzofuran
