171815-45-5

Upstream product

• 171815-43-3 Acetic acid (3aS,4R,6S,7R,7aS)-7-(tert-butyl-diphenyl-silanyloxy)-2,2-dimethyl-6-phenylsulfanyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-ylmethyl ester 
• 171815-42-2 phenyl 6-O-acetyl-3,4-O-isopropylidene-1-thio-β-D-galactopyranoside 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Relevant academic research and scientific papers

Chemical and enzymatic diastereoselective cleavage of β-D galactopyranosylsulfoxides

The self induced diastereoselective oxidation of several thio-β-D- galactopyranosides to the corresponding sulfoxides, has been shown to occur in high yield. Up to 74% diastereomeric excess could be obtained depending on the structure and the conformation of the starting thioglycoside. Rs and Ss Phenylsulfinyl-β-D-galactopyranosides have been obtained in optically pure forms, their chemical as well as enzymatic hydrolysis with triflic acid and with β-galactosidase have been shown to proceed diastereoselectively, the structure of the sulfoxide 4'S with the S configuration at the sulfinyl sulfur has been determined by X-ray analysis.