UC1023, also known as 1-(3-chlorophenyl)-3-(4-fluorophenyl)-1-(4-phenyl-4H-1,2,4-triazol-3-yl)-2-propen-1-one, is a chemical compound with a molecular formula of C22H16ClFN2O and a molecular weight of 378.82 g/mol. It is a white to off-white crystalline powder with a melting point of 90-92°C. UC1023 is a potent and selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4), which plays a crucial role in the regulation of glucose homeostasis. By inhibiting DPP-4, UC1023 can prolong the action of incretin hormones, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), leading to improved glucose control in the body. This makes UC1023 a potential therapeutic agent for the treatment of type 2 diabetes and other metabolic disorders.
The CAS Registry Mumber 17182-23-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,1,8 and 2 respectively; the second part has 2 digits, 2 and 3 respectively. Calculate Digit Verification of CAS Registry Number 17182-23: (7*1)+(6*7)+(5*1)+(4*8)+(3*2)+(2*2)+(1*3)=99 99 % 10 = 9 So 17182-23-9 is a valid CAS Registry Number.