171877-91-1

Basic information

• Product Name: 3-(6-AMINO-9H-PURIN-9-YL)-2,5-ANHYDRO-3-DEOXY-L-MANNITOL
• Synonyms: 3-(6-AMINO-9H-PURIN-9-YL)-2,5-ANHYDRO-3-DEOXY-L-MANNITOL
• CAS NO: 171877-91-1
• Molecular Formula: C11H15N5O4
• Molecular Weight: 281.271
• Mol File: 171877-91-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(6-AMINO-9H-PURIN-9-YL)-2,5-ANHYDRO-3-DEOXY-L-MANNITOL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(6-AMINO-9H-PURIN-9-YL)-2,5-ANHYDRO-3-DEOXY-L-MANNITOL(171877-91-1)
• EPA Substance Registry System: 3-(6-AMINO-9H-PURIN-9-YL)-2,5-ANHYDRO-3-DEOXY-L-MANNITOL(171877-91-1)

Safety Data

• Hazardous Substances Data: 171877-91-1(Hazardous Substances Data)

Upstream product

• 495-75-0 2,5-anhydro-D-mannose 
• 41107-82-8 2,5-anhydro-D-mannitol 
• 1078691-95-8 (+)-D-glucosamine hydrochloride 
• 91318-12-6 2,5:3,4-dianhydro-1,6-di-O-benzoyl-D-altritol 
• 66224-66-6 adenine 
• 196596-83-5 3-O-p-tolylsulfonyl-2,5-anhydro-L-idofuranose dimethylacetal 
• 171877-93-3 4-deoxy-4-(adenin-9-yl)-2,5-anhydro-L-mannofuranose dimethylacetal 
• 86363-73-7 (2R,3S,4S,5R)-3,4-dihydroxy(tetrahydrofuran-2,5-diyl)bis(methylene) dibenzoate 
• 171877-92-2 2,5:3,4-dianhydro-L-talofuranose dimethylacetal 

Relevant articles and documents

Synthesis of 3-deoxy-3-nucleobase-2,5-anhydro-D-mannitol: A novel class of hydroxymethyl-branched isonucleosides

A concise synthesis of 3-deoxy-3-nucleobase-2,5-anhydro-D-mannitol 6(a- d) has been achieved, using the deamination of 2-amino-2-deoxy-D-glucose to construct in one step the sugar skeleton with the desired sense of chirality at each asymmetric center. The selective dibenzoylation of 2,5-anhydro-D- mannitol 9 was investigated, and the key epoxide intermediate 13 was obtained in good yield via an intramolecular Mitsunobu reaction. The process of opening of epoxide 13 by nucleobases appeared to be regioselective. (C) 2000 Elsevier Science Ltd.