17193-43-0 Usage
General Description
(S)-2-Amino-3-(4-methoxyphenyl)propionic acid ethyl ester, also known as S-Naproxen, is a chemical compound that belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). It is used to relieve pain, inflammation, and stiffness caused by conditions such as arthritis, menstrual cramps, and other musculoskeletal conditions. S-Naproxen works by inhibiting the production of prostaglandins, which are chemicals in the body that cause inflammation and pain. It is available in various forms, including tablets, suspension, and extended-release tablets, and is often prescribed by a healthcare professional to be taken with food or milk to reduce the risk of stomach upset. Like other NSAIDs, S-Naproxen may cause side effects such as stomach bleeding, ulcers, and kidney problems, and should be used with caution, especially in individuals with a history of gastrointestinal issues or cardiovascular disease.
Check Digit Verification of cas no
The CAS Registry Mumber 17193-43-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,1,9 and 3 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 17193-43:
(7*1)+(6*7)+(5*1)+(4*9)+(3*3)+(2*4)+(1*3)=110
110 % 10 = 0
So 17193-43-0 is a valid CAS Registry Number.
17193-43-0Relevant articles and documents
Rh(iii)-Catalyzed diastereoselective transfer hydrogenation: An efficient entry to key intermediates of HIV protease inhibitors
Chen, Gen-Qiang,Lang, Qi-Wei,Phansavath, Phannarath,Ratovelomanana-Vidal, Virginie,Wang, Fangyuan,Wu, Ting,Yin, Congcong,Zhang, Xumu,Zheng, Long-Sheng
supporting information, p. 3119 - 3122 (2020/03/23)
A highly efficient diastereoselective transfer hydrogenation of α-aminoalkyl α′-chloromethyl ketones catalyzed by a tethered rhodium complex was developed and successfully utilized in the synthesis of the key intermediates of HIV protease inhibitors. With the current Rh(iii) catalyst system, a series of chiral 3-amino-1-chloro-2-hydroxy-4-phenylbutanes were produced in excellent yields and diastereoselectivities (up to 99% yield, up to 99?:?1 dr). Both diastereomers of the desired products could be efficiently accessed by using the two enantiomers of the Rh(iii) catalyst.
