17207-48-6

Upstream product

• 5326-50-1 (1-hydroxycyclohexyl)acetic acid ethyl ester 
• 100-47-0 benzonitrile 

Downstream Products

• 51219-66-0 2-phenyl-3-oxa-1-aza-spiro[5.5]undec-1-en-4-one 
• 51219-67-1 1-Benzoylaminocyclohexylacetyl-β-aminoisovaleriansaeuremethylester 

Relevant academic research and scientific papers

FUSED QUINOLINE DERIVATIVE AND USE THEREOF

The present invention aims at provision of a quinoline derivative having a neurokinin 2 (NK2) receptor antagonistic action and relates to a compound represented by the formula (I) wherein Rl is a hydrogen atom and the like; R2 is a hydrogen atom, a hydrocarbon group optionally having substituent(s) and the like; R3 is unsubstituted (i.e., absence), a hydrogen atom and the like; R4 and R5 are the same or different and each is a hydrogen atom, a hydrocarbon group optionally having substituent(s), and the like; R6is (cyclic group optionally having substituent(s)) -carbonyl, and the like; R7, R8,R9 and R10 are the same or different and each is a hydrogen atom, halogen and the like; or R7and R8,R8 and R9,and R9 and R10 may form a ring together with the adjacent carbon atoms; n is an integer of 1 to 5; --- represents unsubstituted (i.e., absence) or a single bond; and --- represents a single bond or a double bond, or a salt thereof, and the like.