172088-73-2Relevant academic research and scientific papers
Inhibition of E-selectin-, ICAM-1-, and VCAM-1-mediated cell adhesion by benzo[b]thiophene-, benzofuran-, indole-, and naphthalene-2-carboxamides: Identification of PD 144795 as an antiinflammatory agent
Boschelli,Kramer,Khatana,Serenson,Connor,Ferin,Wright,Lesch,Imre,Okonkwo,Schrier,Conroy,Ferguson,Woelle,Saxena
, p. 4597 - 4614 (1995)
It was previously reported that 3-alkoxybenzo[b]thiophene-2-carboxamides exemplified by 1, 5-methoxy-3-(1-methylethoxy)benzo[b]thiophene-2- carboxamide, decreased the adherence of neutrophils to activated endothelial cells by inhibiting the upregulation o
3-alkyloxy-, aryloxy-, or arylalkyloxy-benzo [β]thiophene-2-carboxamides as inhibitors of cell adhesion
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, (2008/06/13)
3-Alkyloxy-, aryloxy-, or arylalkyloxybenzo[b]-thiophene-2-carboxamides are described as agents which block leukocyte adherence to vascular endothelium and, as such, are effective therapeutic agents for treating inflammatory diseases. Certain of these compounds are novel and methods of preparation are also described.
