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<2H7>-acrivastine, also known as Acrivastine-d7, is the isotope-labelled analog of Acrivastine (A191180). It is a compound derived from the allergy medication and histamine H2 antagonist, Acrivastine. The presence of deuterium (2H or D) in its molecular structure distinguishes it from the parent compound, making it useful for various applications in research and pharmaceutical development.

172165-56-9

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172165-56-9 Usage

Uses

Used in Pharmaceutical Research:
<2H7>-acrivastine is used as a research tool for studying the pharmacokinetics, metabolism, and distribution of Acrivastine in the body. The incorporation of deuterium allows for a more accurate analysis of the compound's behavior in biological systems, as it can be easily distinguished from the non-labelled parent compound.
Used in Drug Development:
<2H7>-acrivastine serves as a valuable compound in the development of new drugs with improved properties. By understanding the interactions and effects of the isotope-labelled analog, researchers can gain insights into the structure-activity relationships of Acrivastine and potentially design more effective histamine H2 antagonists or other allergy medications.
Used in Allergy Medication:
<2H7>-acrivastine is used as an isotope-labelled analog in the development and optimization of allergy medications. Its application in this field can help researchers understand the mechanisms of action and potential side effects of Acrivastine, leading to the creation of safer and more effective treatments for allergic reactions.
Used in Histamine H2 Antagonist Research:
<2H7>-acrivastine is used as a research compound to study the interactions between histamine H2 antagonists and their target receptors. This information can be crucial in the development of new histamine H2 antagonists with improved efficacy and reduced side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 172165-56-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,2,1,6 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 172165-56:
(8*1)+(7*7)+(6*2)+(5*1)+(4*6)+(3*5)+(2*5)+(1*6)=129
129 % 10 = 9
So 172165-56-9 is a valid CAS Registry Number.

172165-56-9Downstream Products

172165-56-9Relevant academic research and scientific papers

SYNTHESIS OF DEUTERIUM-LABELED ACRIVASTINE AND AN ACRIVASTINE METABOLITE

Thompson, J.B.,Blake, K.W.,McNutt, R.W.

, p. 972 - 980 (2007/10/02)

The antihistamine acrivastine and a metabolite dihydroacrivastine were prepared as their -congeners from -tolualdehyde for use as internal standards in gas chromatography/mass spectroscopy of biological samples.Key words: acrivastine, antihistam

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