Dideguanyl-dihydrostreptomycin is a semi-synthetic aminoglycoside antibiotic derived from the parent compound, streptomycin. It is characterized by the removal of two guanidinium groups and the reduction of the streptose sugar, resulting in enhanced stability and reduced toxicity compared to its parent compound. This antibiotic exhibits bactericidal activity by binding to the 30S ribosomal subunit of bacteria, inhibiting protein synthesis and leading to cell death. It is particularly effective against a range of Gram-negative bacteria, including some strains of Escherichia coli and Klebsiella pneumoniae, and is used to treat various bacterial infections. However, its use is often limited due to the potential for ototoxicity and nephrotoxicity, which are common side effects of aminoglycoside antibiotics.
The CAS Registry Mumber 1722-48-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,2 and 2 respectively; the second part has 2 digits, 4 and 8 respectively. Calculate Digit Verification of CAS Registry Number 1722-48: (6*1)+(5*7)+(4*2)+(3*2)+(2*4)+(1*8)=71 71 % 10 = 1 So 1722-48-1 is a valid CAS Registry Number.
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