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2-naphthalen-2-ylsulfanylethanol, also known as 2-(2-naphthylthio)ethanol, is a chemical compound with the molecular formula C12H12OS. It is a thiol compound characterized by the presence of a naphthalene ring. 2-naphthalen-2-ylsulfanylethanol is recognized for its utility in organic synthesis and pharmaceutical research, where it serves as a building block for the creation of various organic molecules. Its synthesis can be achieved through the reaction of 2-naphthalenethiol with epichlorohydrin, and it is capable of undergoing further reactions to yield a range of different derivatives. Additionally, 2-naphthalen-2-ylsulfanylethanol is employed as a chiral auxiliary in asymmetric synthesis, which underscores its value in the realm of organic chemistry.

17225-95-5

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17225-95-5 Usage

Uses

Used in Organic Synthesis:
2-naphthalen-2-ylsulfanylethanol is used as a building block in organic synthesis for the creation of various organic molecules. Its structural features make it a versatile component in the construction of complex molecules.
Used in Pharmaceutical Research:
In pharmaceutical research, 2-naphthalen-2-ylsulfanylethanol is utilized as a key intermediate in the development of new drugs. Its ability to form a wide array of derivatives allows for the exploration of potential therapeutic agents.
Used in Asymmetric Synthesis:
2-naphthalen-2-ylsulfanylethanol is used as a chiral auxiliary in asymmetric synthesis. This application is crucial for the production of enantiomerically pure compounds, which is essential in many pharmaceutical and chemical applications where the stereochemistry of a molecule can significantly influence its biological activity and efficacy.
Used in Chemical Production:
2-naphthalen-2-ylsulfanylethanol is used in the production of various chemical products. Its synthesis through the reaction of 2-naphthalenethiol with epichlorohydrin is a key step in the manufacturing process of certain specialty chemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 17225-95-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,2,2 and 5 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 17225-95:
(7*1)+(6*7)+(5*2)+(4*2)+(3*5)+(2*9)+(1*5)=105
105 % 10 = 5
So 17225-95-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H12OS/c13-7-8-14-12-6-5-10-3-1-2-4-11(10)9-12/h1-6,9,13H,7-8H2

17225-95-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-naphthalen-2-ylsulfanylethanol

1.2 Other means of identification

Product number -
Other names (2-Hydroxy-aethyl)-(naphthyl-(2))-sulfid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:17225-95-5 SDS

17225-95-5Synthetic route

2-Naphthalenethiol
91-60-1

2-Naphthalenethiol

2-chloro-ethanol
107-07-3

2-chloro-ethanol

2-(2-naphthylthio)ethanol
17225-95-5

2-(2-naphthylthio)ethanol

Conditions
ConditionsYield
With potassium hydroxide at 60 - 100℃;
2-(2-naphthylthio)ethanol
17225-95-5

2-(2-naphthylthio)ethanol

C33H27NO4S
144127-62-8

C33H27NO4S

Conditions
ConditionsYield
With 18-crown-6 ether; caesium carbonate In acetonitrile at 25℃; for 45h;85%
2-(2-naphthylthio)ethanol
17225-95-5

2-(2-naphthylthio)ethanol

(2-chloroethyl)(naphthalen-2-yl)sulfide
35374-43-7

(2-chloroethyl)(naphthalen-2-yl)sulfide

Conditions
ConditionsYield
With phosphorus pentachloride
2-(2-naphthylthio)ethanol
17225-95-5

2-(2-naphthylthio)ethanol

2-(naphthalene-2-sulfonyl)-ethanol
100519-04-8

2-(naphthalene-2-sulfonyl)-ethanol

Conditions
ConditionsYield
With sodium hydroxide; sodium hypochlorite
2-(2-naphthylthio)ethanol
17225-95-5

2-(2-naphthylthio)ethanol

β-naphthyl 2-chloroethyl sulfone
90395-98-5

β-naphthyl 2-chloroethyl sulfone

Conditions
ConditionsYield
With hydrogenchloride; sodium hypochlorite
2-(2-naphthylthio)ethanol
17225-95-5

2-(2-naphthylthio)ethanol

1.25 mol PCl5

1.25 mol PCl5

(2-chloroethyl)(naphthalen-2-yl)sulfide
35374-43-7

(2-chloroethyl)(naphthalen-2-yl)sulfide

2-(2-naphthylthio)ethanol
17225-95-5

2-(2-naphthylthio)ethanol

PCl5 (excess)

PCl5 (excess)

<2-chloro-ethyl>--sulfide

<2-chloro-ethyl>--sulfide

17225-95-5Relevant academic research and scientific papers

Dynemicin analogs: syntheses, methods of preparation and use

-

, (2008/06/13)

A fused ring system compound is disclosed that contains an epoxide group on one side of the fused rings and an enediyne macrocyclic ring on the other side of the fused rings. The compounds have DNA-cleaving, antimicrobial and tumor growth-inhibiting properties. Chimeric compounds having the fused ring system compound as an aglycone bonded to (i) a sugar moiety as the oligosaccharide portion or (ii) a monoclonal antibody or antibody combining site portion thereof that immunoreacts with target tumor cells are also disclosed. Compositions containing a compound or a chimer are disclosed, as are methods of preparing a compound.

Dynemicin analogs: synthesis, methods of preparation and use

-

, (2008/06/13)

A fused ring system compound is disclosed that contains an epoxide group on one side of the fused rings and an enediyne macrocyclic ring on the other side of the fused rings. The compounds have DNA-cleaving, antimicrobial and tumor growth-inhibiting properties. Chimeric compounds having the fused ring system compound as an aglycone bonded to (i) a sugar moiety as the oligosaccharide portion or (ii) a monoclonal antibody or antibody combining site portion thereof that immunoreacts with target tumor cells are also disclosed. Compositions containing a compound or a chimer are disclosed, as are methods of preparing a compound.

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