172275-58-0Relevant articles and documents
(2R,3S)- and (2S,3R)-2-benzyl-3,4-epoxybutanoic acid as highly efficient and fast acting pseudomechanism-based inactivators for carboxypeptidase A: design, asymmetric synthesis and inhibitory kinetics
Lee, Soo Suk,Li, Zhi-Hong,Lee, Dong Ha,Kim, Dong H.
, p. 2877 - 2882 (2007/10/02)
2-benzyl-3,4-epoxybutanoic acid (BEBA) was studied as an irreversible inhibitor for the zinc-containing protease, carboxypeptidase A.Of four possible stereoisomers, those having a 2R,3S- and a 2S,3R- configuration inhibited carboxypeptidase A in a time-de