172374-00-4

Basic information

• Product Name: (1R,2R,3S,4S)-<3--2-bornyl>-(1S,5R)-5-(5-tert-butyl-diphenyl-silyloxy-1-penten-2-yl)-2-oxo-cyclopentanecarboxylate
• Synonyms: (1R,2R,3S,4S)-<3--2-bornyl>-(1S,5R)-5-(5-tert-butyl-diphenyl-silyloxy-1-penten-2-yl)-2-oxo-cyclopentanecarboxylate
• CAS NO: 172374-00-4
• Molecular Weight: 846.216
• Mol File: 172374-00-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2R,3S,4S)-<3--2-bornyl>-(1S,5R)-5-(5-tert-butyl-diphenyl-silyloxy-1-penten-2-yl)-2-oxo-cyclopentanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R,3S,4S)-<3--2-bornyl>-(1S,5R)-5-(5-tert-butyl-diphenyl-silyloxy-1-penten-2-yl)-2-oxo-cyclopentanecarboxylate(172374-00-4)
• EPA Substance Registry System: (1R,2R,3S,4S)-<3--2-bornyl>-(1S,5R)-5-(5-tert-butyl-diphenyl-silyloxy-1-penten-2-yl)-2-oxo-cyclopentanecarboxylate(172374-00-4)

Safety Data

• Hazardous Substances Data: 172374-00-4(Hazardous Substances Data)

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 64180-78-5 4-bromopent-4-en-1-ol 
• 161551-45-7 ((4-bromopent-4-en-1-yl)oxy)(tert-butyl)diphenylsilane 
• 172490-96-9 (1R,2R,3S,4S)-<3--2-bornyl>-2-oxo-cyclopentene-carboxylate 
• 594-19-4 tert.-butyl lithium 

Downstream Products

• 172490-98-1 (1R,2S,3R)-3-(5-tert-butyldiphenylsilyloxy-1-penten-2-yl)-1,2-dimethyl-cyclopentanol 
• 172374-02-6 ethyl (1R,5S)-5-(5-tert-butyldiphenyl-silyloxy-1-penten-2-yl)-1-methyl-2-oxo-cyclopentanecarboxylate 
• 172490-97-0 (2S,3R)-3-(5-tert-butyldiphenylsilyloxy-1-penten-2-yl)-2-methyl-cyclopentanone 
• 99877-51-7 4-(3-hydroxy-2,3-dimethyl-cyclopentyl)-pent-4-ene-1-ol 
• 87360-02-9 N-(3,5-Dimethyl-phenyl)-N-((1S,2S,3R,4R)-3-hydroxy-4,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl)-benzenesulfonamide 
• 172374-01-5 ethyl (1S,5R)-5-<(5-tert-butyldiphenylsilyloxy)-1-penten-2-yl>-2-oxo-cyclopentanecarboxylate 

Relevant articles and documents

A Short Synthesis of (-)-Chokol A

(-)-Chokol A (10) was prepared in six steps (22 percent overall yield) via conjugate addition of a higher order cyanocuprate to the chiral 2-oxo-cyclopentenecarboxylate 2n.After deprotection by transesterification the enantiomerically pure β-ketoester 5 was obtained which was transformed by α-methylation and subsequent decarbethoxylation to the cyclopentanone derivative 8.Addition of methylcerium dichloride resulted in a mixture of 9a, 9b and 9c (78:16:6), from which the main diastereomer 9a was separated by MPLC.Finally desilylation of 9a achieved (-)-chokol A (10).