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17243-57-1

17243-57-1

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17243-57-1 Usage

Originator

Pondinil,Roche,France,1970

Uses

Anorexic.

Manufacturing Process

9.5 parts of β-chloropropionaldehyde were added slowly, at a temperature of 0°C to a solution of 31.5 parts of 1-phenyl-2-aminopropane in 150 parts of methanol. Thereafter, 0.2 part of platinum oxide was added to the reaction mixture following which the mixture was reacted with hydrogen, in a shaking vessel, until the theoretical quantity of hydrogen had been taken up. When the hydrogenation reaction was completed, the catalyst was removed by filtration and the filtrate neutralized with hydrochloric acid. Subsequently, the filtrate was evaporated to dryness and recrystallized from isopropyl alcohol. The thus-obtained N-(3-chloropropyl)-α-methylphenethylamine hydrochloride melted at 128°C to 130°C.

Therapeutic Function

Anorexic

Check Digit Verification of cas no

The CAS Registry Mumber 17243-57-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,2,4 and 3 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 17243-57:
(7*1)+(6*7)+(5*2)+(4*4)+(3*3)+(2*5)+(1*7)=101
101 % 10 = 1
So 17243-57-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H18ClN/c1-11(14-9-5-8-13)10-12-6-3-2-4-7-12/h2-4,6-7,11,14H,5,8-10H2,1H3

17243-57-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Mefenorex

1.2 Other means of identification

Product number -
Other names N-(3-chloropropyl)-1-phenylpropan-2-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:17243-57-1 SDS

17243-57-1Upstream product

17243-57-1Downstream Products

17243-57-1Related news

Studies on the metabolism and toxicological detection of the amphetamine-like anorectic mefenorex (cas 17243-57-1) in human urine by gas chromatography–mass spectrometry and fluorescence polarization immunoassay108/26/2019

Studies on the metabolism and on the toxicological analysis of mefenorex [R,S-N-(3-chloropropyl)-α-methylphenethylamine, MF] using gas chromatography–mass spectrometry (GC–MS) and fluorescence polarization immunoassay (FPIA) are described. The metabolites were identified in urine samples of v...detailed

ArticleEffect of mefenorex (cas 17243-57-1) on 5-HT release: Studies in vitro on rat hypothalamic slices and in vivo by microdialysis08/25/2019

Mefenorex, used for 20 years as an anorexic drug, has not been studied so far with regard to its central mechanism of action, although its chemical structure suggests a serotonergic mechanism. In the present study, the effect of mefenorex on serotonin (5-HT) release was investigated both in vitr...detailed