172477-99-5 Usage
Uses
Used in Pharmaceutical Industry:
(1-Benzyl-piperidin-3-yl)-methyl-carbamic acid tert-butyl ester is used as a building block for the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be incorporated into a wide range of drug molecules, making it a valuable component in the development of new medications.
Used in Agrochemical Industry:
In the agrochemical industry, (1-Benzyl-piperidin-3-yl)-methyl-carbamic acid tert-butyl ester is used as a building block for the synthesis of various agrochemicals. Its versatility in chemical reactions enables it to be used in the development of pesticides, herbicides, and other agricultural chemicals.
Used in Materials Science:
(1-Benzyl-piperidin-3-yl)-methyl-carbamic acid tert-butyl ester is also used in the field of materials science. Its unique properties make it suitable for the synthesis of various materials with specific characteristics, such as polymers, coatings, and adhesives.
Used as a Protecting Group in Organic Synthesis:
In organic synthesis, (1-Benzyl-piperidin-3-yl)-methyl-carbamic acid tert-butyl ester serves as a protecting group for amines. This allows chemists to carry out reactions on other functional groups in a molecule without affecting the amine group, which can be deprotected later to reveal the original amine functionality. This technique is crucial in the synthesis of complex organic molecules and the development of new chemical compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 172477-99-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,2,4,7 and 7 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 172477-99:
(8*1)+(7*7)+(6*2)+(5*4)+(4*7)+(3*7)+(2*9)+(1*9)=165
165 % 10 = 5
So 172477-99-5 is a valid CAS Registry Number.
172477-99-5Relevant academic research and scientific papers
SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1
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Page/Page column 565, (2018/01/20)
The invention is directed to substituted pyridine derivatives. Specifically, the invention is directed to compounds according to Formula (Iar): (Iar) wherein Yar, X1ar, X2ar, R1ar, R2ar, R3ar, R4ar and R5ar are as defined herein; or a pharmaceutically acceptable salt or prodrug thereof. The compounds of the invention are selective inhibitors of DNMT1 and can be useful in the treatment of cancer, pre-cancerous syndromes, beta hemoglobinopathy disorders, sickle cell disease, sickle cell anemia, and beta thalassemia, and diseases associated with DNMT1 inhibition. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting DNMT1 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.
Monocyclic Analogues of the μ-Opioid Agonist 3,8-Diazabicyclooctanes: Synthesis, Modeling, and Activity
Barlocco, Daniela,Villa, Stefania,Fratta, Walter,Fadda, Paola,Colombo, Diego,Toma, Lucio
, p. 11547 - 11556 (2007/10/02)
Several monocyclic derivatives structurally related to the μ-opioid agonist 3-cinnamyl-8-propionyl-3,8-diazabicyclooctane have been synthesized and tested in binding studies using the μ-selective 3H-DAMGO as ligand.Modeling studies have been performed on the same compounds in order to explain the observed lack of affinity towards μ-opioid receptors.
