172505-34-9

Upstream product

• 109-72-8 n-butyllithium 
• 172490-96-9 (1R,2R,3S,4S)-<3--2-bornyl>-2-oxo-cyclopentene-carboxylate 
• 87360-02-9 N-(3,5-Dimethyl-phenyl)-N-((1S,2S,3R,4R)-3-hydroxy-4,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl)-benzenesulfonamide 
• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 

Relevant academic research and scientific papers

Enatiomerically pure 5-substituted 2-oxo-cyclopentanecarboxylates by conjugate addition of cuprates to asymmetry shielded 2-oxo-cyclopentenecarboxylates

Asymmetric shielded 2-oxo-cyclopentenecarboxylates 6n and 6x were prepared by transesterification of 2-oxo-cyclopentanecarboxylate 2 with camphor derived concave alcohols 1n and 1x and by subsequent introduction of a double bond via phenylselenides. Diastereoselective conjugate addition of equimolar amounts of mixed cuprates at -78°C and deprotection by ethanolysis gave enantiomerically pure 5-substituted 2-oxo-cyclopentanecarboxylates 13-18 and ent-13-18, valuable as chiral building blocks in natural product synthesis.

EPC synthesis of 5-substituted 2-oxo-cyclopentanecarboxylates via conjugate addition of cuprates to asymmetric shielded 2-oxo-cyclopentenecarboxylates

Asymmetric shielded 2-oxo-cyclopentenecarboxylates 6n and 6x were prepared by trans-esterification of 2-oxo-cyclopentanecarboxylate 2 with camphor derived concave alcohols 1n and 1x and by subsequent introduction of a double bond via phenylselenides. Dias