172511-85-2Relevant academic research and scientific papers
A new strategy for the stereoselective synthesis of 2,2′-bipyrrolidines
Gresser, Mary J.,Keller, Paul A.,Wales, Steven M.
scheme or table, p. 4899 - 4902 (2009/12/05)
A new strategy for the stereoselective synthesis of the 2,2′-bipyrrolidine scaffold is presented using a metathesis reaction followed by asymmetric dihydroxylation for the introduction of the stereogenic elements. This straightforward high-yielding process is suitable for application to the synthesis of additional heterocycles.
New Convenient, Enantiospecific Synthesis of (S,S)- and (R,R)-2,2'-Bipyrrolidine Derivatives
Kotsuki, Hiyoshizo,Kuzume, Hiroko,Gohda, Tetsushi,Fukuhara, Misako,Ochi, Masamitsu,et al.
, p. 2227 - 2236 (2007/10/03)
An enantiomer pair of (S,S)- and (R,R)-bipyrrolidine derivatives has been prepared from D- and L-tartaric acids or D-mannitol as optically active starting materials.Taking advantage of the C2-symmetric nature of these chiral sources, the synthe
