172540-17-9

Upstream product

• 172540-12-4 3-(benzyloxy)-5-methyl-4-isoxazolecarbonyl chloride 
• 172540-13-5 3-(benzyloxy)-5-methyl-4-isoxazolecarbaldehyde 
• 115886-03-8 3-(benzyloxy)-5-methyl-4-isoxazolecarboxylic acid 
• 172540-15-7 N-[(S)-(3-Benzyloxy-5-methyl-isoxazol-4-yl)-tert-butylcarbamoyl-methyl]-N-((S)-1-phenyl-ethyl)-benzamide 

Relevant academic research and scientific papers

N-methyl-D-aspartic acid receptor agonists: Resolution, absolute stereochemistry, and pharmacology of the enantiomers of 2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid

(R,S)-2-Amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid [(R,S)-AMAA, 4] is a potent and selective agonist at the N-methyl-D-aspartic acid (NMDA) subtype of excitatory amino acid receptors. Using the Ugi "four-component condensation" method, the two d