172588-77-1

Basic information

• Product Name: 1H-Indene-1,2-diol, 2,3-dihydro-, (1S,2S)-
• CAS NO: 172588-77-1
• Molecular Formula: C9H10O2
• Molecular Weight: 150.177
• Mol File: 172588-77-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-Indene-1,2-diol, 2,3-dihydro-, (1S,2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indene-1,2-diol, 2,3-dihydro-, (1S,2S)-(172588-77-1)
• EPA Substance Registry System: 1H-Indene-1,2-diol, 2,3-dihydro-, (1S,2S)-(172588-77-1)

Safety Data

• Hazardous Substances Data: 172588-77-1(Hazardous Substances Data)

Upstream product

• 768-22-9 2,3-epoxyindene 
• 109296-68-6 1-hydroxy-2-indanone 
• 6932-79-2 1-bromo-indan-2-one 
• 4370-02-9 trans-indane-1,2-diol 
• 10368-44-2 trans-2-bromo-1-indanol 
• 4254-29-9 indan-2-ol 
• 95-13-6 1-indene 

Downstream Products

• 136030-00-7 (1R,2S)-1-Amino-2-indanol 

Relevant articles and documents

SYNTHESIS AND APPLICATION OF CHIRAL SUBSTITUTED POLYVINYLPYRROLIDINONES

Chiral polyvinylpyrrolidinone (CSPVP), complexes of CSPVP with a core species, such as a metallic nanocluster catalyst, and enantioselective oxidation reactions utilizing such complexes are disclosed. The CSPVP complexes can be used in asymmetric oxidation of diols, enantioselective oxidation of alkenes, and carbon-carbon bond forming reactions, for example. The CSPVP can also be complexed with biomolecules such as proteins, DNA, and RNA, and used as nanocarriers for siRNA or dsRNA delivery.

Biocatalysis of Deracemization in 1,2-Diols

The fungus Corynosporium cassicola DSM 62475 is shown to induce deracemization in certain 1,2-diols, including the synthetically important indane-1,2-diol, by enantioconvergent stereoinversion processes in which the recovered enantiomer is not a substrate for the dehydrogenase enzymes involved.

Microbiological transformations. 31: Synthesis of enantiopure epoxides and vicinal diols using fungal epoxide hydrolase mediated hydrolysis

The enantioselective hydrolysis of epoxyindene and dihydronaphtalene epoxides by the fungus Beauveria sulfurescens (ATCC 7159) is described. This allowed the preparation of both these epoxides, as well as of the corresponding diols, in good to excellent enantiomeric purity.