172599-63-2Relevant academic research and scientific papers
Highly water-soluble and tumor-targeted photosensitizers for photodynamic therapy
Li, Yuxi,Wang, Jin,Zhang, Xiaoxiao,Guo, Wenjun,Li, Fu,Yu, Min,Kong, Xiuqi,Wu, Wenjie,Hong, Zhangyong
, p. 7681 - 7694 (2015)
Biological uses of photosensitizers in photodynamic therapy (PDT) often suffer from a lack of tumor selectivity; a strategy based on molecule-targeted cancer therapies could provide a promising solution. To synthesize new water-soluble phthalocyanines (Pc
Design of Turn-On Near-Infrared Fluorescent Probes for Highly Sensitive and Selective Monitoring of Biopolymers
Ducharme, Gerard T.,LaCasse, Zane,Nesterov, Evgueni E.,Nesterova, Irina V.,Sheth, Tanya
, p. 8440 - 8444 (2020)
Simple, sensitive, and selective detection of specific biopolymers is critical in a broad range of biomedical and technological areas. We present a design of turn-on near-infrared (NIR) fluorescent probes with intrinsically high signal-to-background ratio
In vitro and in vivo evaluation of improved EGFR targeting peptide-conjugated phthalocyanine photosensitizers for tumor photodynamic therapy
Chen, Qingle,Ma, Yanhong,Zhao, Jisi,Zhao, Mei,Li, Wenjing,Liu, Qian,Xiong, Li,Wu, Wenjie,Hong, Zhangyong
, p. 1171 - 1178 (2018)
Phthalocyanine (Pc) is one of the most promising photosensitizer candidates because of its strong absorption (extinction coefficient ε > 105 L mol?1 cm?1) at long wavelengths and strong singlet oxygen generation abilities
COLORANT AND COMPOSITION COMPRISING THE COLORANT
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Paragraph 0058-0059, (2020/04/09)
An objective of the present invention is to provide a colorant which is physicochemically stable and exhibits excellent color intensity. According to the colorant and a composition comprising the same of the present invention, the colorant has a structure
Synthesis and biological evaluation of peptide-conjugated phthalocyanine photosensitizers with highly hydrophilic modifications
Li, Fu,Liu, Qian,Liang, Zhenzhen,Wang, Jin,Pang, Mingpei,Huang, Weiqiang,Wu, Wenjie,Hong, Zhangyong
supporting information, p. 3409 - 3422 (2016/04/09)
The selectivity of targeted photosensitizer delivery is a constant challenge for photodynamic therapy (PDT). Herein, with the aim of optimizing the affinity, selectivity and activity of peptide-conjugated photosensitizers for PDT therapy and fluorescence
Solid-phase synthesis of asymmetrically substituted "AB 3-Type" phthalocyanines
Erdem, S. Sibel,Nesterova, Irina V.,Soper, Steven A.,Hammer, Robert P.
, p. 5003 - 5007 (2008/12/20)
(Chemical Equation Presented) Synthesis of phthalocyanines with asymmetrical substitution on the periphery is often difficult due the problems in purification of the phthalocyanine mixtures obtained. Using a poly(ethylene glycol) (PEG)-based support with
TETRAAZAPORPHYRIN-BASED COMPOUNDS AND THEIR USES
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Page/Page column 35, (2008/06/13)
Asymmetrically substituted metal-phthalocyanine compounds are disclosed. These compounds and other phthalocyanine-derivatives are used in bioimaging, bioanalysis, FRET and quenching techniques, photodynamic therapy, DNA analysis for cells, proteins, tissues and other biological entities, and other applications. Near- infrared fluorescence minimizes matrix effects typically seen in other methods of analyzing biochemical entities in cells, proteins, tissues and other biological entities.
