1726-77-8Relevant academic research and scientific papers
Formation of potentially toxic carbonyls during oxidation of triolein in the presence of alimentary antioxidants
Damanik, Marini,Murkovic, Michael
, p. 2031 - 2035 (2017/10/26)
Abstract: A relation between oil uptake and cancer as well as induction of hepatic inflammation was shown earlier. It is discussed that the main oil oxidation products—hydroperoxides and carbonyls—might be the reason for the mentioned diseases. In this manuscript quantitative determination of aldehydes which are formed during oxidation of triolein—as a model substance—using the Rancimat 679 is described. The oxidation of 11?g of triolein is carried out at 120?°C sparging air with a flow of 20?dm3/h for 10?h. A series of aliphatic aldehydes starting from hexanal to decanal as well as decenal was identified by LC–MS/MS and quantified as DNPH derivatives. In addition, the total amount of carbonyls was determined. Based on the calibration with hexanal, all other dominant substances were in the similar concentration range with maximum concentrations of 1.6?μmol/cm3 of hexanal, 2.3?μmol/cm3 of heptanal, 2.5?μmol/cm3 of octanal, 3.2?μmol/cm3 of nonanal, 4.0?μmol/cm3 of decanal after 6?h. The total amount of carbonyls reached a maximum after 6?h being 27?μmol/cm3 for triolein without antioxidant. The results of this investigation will be a basis for further toxicological studies on oxidized oils.
2-Iodoxybenzoic acid organosulfonates: Preparation, X-ray structure and reactivity of new, powerful hypervalent iodine(v) oxidants
Yusubov, Mekhman S.,Svitich, Dmitrii Yu.,Yoshimura, Akira,Nemykin, Victor N.,Zhdankin, Viktor V.
supporting information, p. 11269 - 11271 (2013/12/04)
New powerful hypervalent iodine(v) oxidants, tosylate and mesylate derivatives of 2-iodoxybenzoic acid (IBX), were prepared by the reaction of IBX with the corresponding sulfonic acids. Single crystal X-ray crystallography of the diacetate derivative of IBX-tosylate revealed an unusual heptacoordinated iodine geometry without any significant intermolecular secondary interactions.
Facile preparation and reactivity of polystyrene-supported (dichloroiodo)benzene: A convenient recyclable reagent for chlorination and oxidation
Chen, Jiang-Min,Zeng, Xiao-Mei,Middleton, Kyle,Zhdankin, Viktor V.
supporting information; experimental part, p. 1952 - 1955 (2011/04/25)
A facile one-pot preparation of polystyrene-supported (dichloroiodo)benzene (loading of -ICl2 up to 1.35 mmol/g) from polystyrene, iodine, and bleach has been developed. This recyclable reagent is useful for efficient chlorination of organic substrates and selective oxidation of various alcohols to the corresponding carbonyl compounds in high yields under mild conditions. The final products are conveniently separated from the polymeric byproduct by simple filtration and isolated in good purity after evaporation of solvent.
Analysis of carbonyl compounds in sea buckthorn for the evaluation of triglyceride oxidation, by enzymatic hydrolysis and derivatisation methodology
Mathew, Sindhu,Grey, Carl,Rumpunen, Kimmo,Adlercreutz, Patrick
experimental part, p. 1399 - 1405 (2012/02/03)
Carbonyl compounds formed in sea buckthorn berry (Hippophae rhamnoides) and oil samples as a result of lipid oxidation were determined by enzymatic hydrolysis followed by derivatisation with 2,4-dinitrophenylhydrazine and analysed by LC-UV and electrospra
Highly efficient RuCl3-catalyzed disproportionation of (diacetoxyiodo)benzene to iodylbenzene and iodobenzene; leading to the efficient oxidation of alcohols to carbonyl compounds
Yusubov, Mekhman S.,Chi, Ki-Whan,Park, Joo Yeon,Karimov, Rashad,Zhdankin, Viktor V.
, p. 6305 - 6308 (2007/10/03)
(Diacetoxyiodo)benzene (DIB) selectively oxidizes primary and secondary alcohols to the respective carbonyl compounds in the presence of RuCl3 (0.8-1.0 mol %) at room temperature in aqueous acetonitrile. This reaction proceeds via an initial instantaneous Ru-catalyzed disproportionation of DIB to iodobenzene and iodylbenzene with the latter acting as the actual stoichiometric oxidant toward alcohols.
The Reactivity of Silyl Ethers to the Swern Reagent
Afonso, Carlos M.,Barros, M. Teresa,Maycock, Christopher D.
, p. 1221 - 1224 (2007/10/02)
The activated Me2SO reagent , 'Swern reagent'> oxidises the trimethylsilyl ethers of primary and secondary alcohols directly to the corresponding carbonyl compound.Useful selectivity is possible where competing ether groups possess large differences of steric hindrance.Dimethyl-t-butylsilyl ethers are unaffected by this reagent.
AUTORECYCLING OXIDATION OF AMINES TO CARBONYL COMPOUNDS CATALYZED BY 3,4-DISUBSTITUTED 4-DEAZATOXOFLAVIN DERIVATIVES
Nagamatsu, Tomohisa,Hashiguchi, Yuko,Sakuma, Yoshiharu,Yoneda, Fumio
, p. 1309 - 1312 (2007/10/02)
3,4-Disubstituted 4-deazatoxoflavin derivatives (II) were prepared by the condensation of 6-(1-methylhydrazino)uracils (I) with appropriate α-diketones.The compounds II oxidized long-chain alkylamines such as n-octylamine and n-dodecylamine besides benzylamine and cyclohexylamine to yield the corresponding carbonyl compounds via imines, catalytically with a markedly high turnover number.
