172649-32-0

Basic information

• Product Name: (+/-)-isobornyl 4-(3-cyanophenyl)-2-trifluoromethyl-2-hydroxy-5-oxo-1,2,3,4,5,6,7,8-octahydroquinoline-3-carboxylate
• Synonyms: (+/-)-isobornyl 4-(3-cyanophenyl)-2-trifluoromethyl-2-hydroxy-5-oxo-1,2,3,4,5,6,7,8-octahydroquinoline-3-carboxylate
• CAS NO: 172649-32-0
• Molecular Weight: 516.56
• Mol File: 172649-32-0.mol

Chemical Properties

• CAS DataBase Reference: (+/-)-isobornyl 4-(3-cyanophenyl)-2-trifluoromethyl-2-hydroxy-5-oxo-1,2,3,4,5,6,7,8-octahydroquinoline-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-isobornyl 4-(3-cyanophenyl)-2-trifluoromethyl-2-hydroxy-5-oxo-1,2,3,4,5,6,7,8-octahydroquinoline-3-carboxylate(172649-32-0)
• EPA Substance Registry System: (+/-)-isobornyl 4-(3-cyanophenyl)-2-trifluoromethyl-2-hydroxy-5-oxo-1,2,3,4,5,6,7,8-octahydroquinoline-3-carboxylate(172649-32-0)

Safety Data

• Hazardous Substances Data: 172649-32-0(Hazardous Substances Data)

Downstream Products

• 172649-33-1 (-)-4-(3-cyanophenyl)-2-trifluoromethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid 
• 172649-34-2 (+/-)-isobornyl 4-(3-cyanophenyl)-2-trifluoromethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 

Relevant articles and documents

QUINOLONE DERIVATIVE FOR TREATMENT OF URINARY INCONTINENCE

(S)-(-)-4-(3-cyanophenyl)-2-trifluoromethyl-4,6,7,8-tetrahydro-5(1H)quinolone as a potassium channel opener, useful for treating urinary incontinence, and processes for the preparation thereof.

Heterocyclic derivatives

Compounds of formula I STR1 wherein R2, R3, R4, R10 and R11 have any of the meanings given in the specification, and their pharmaceutically acceptable salts are useful in the treatment of urinery incontinence. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula I and intermediates.