172660-93-4Relevant academic research and scientific papers
A facile synthesis of carboxamides by dehydration condensation between free carboxylic acids and amines using O,O′-DI(2-pyridyl) thiocarbonate as a coupling reagent
Shiina, Isamu,Saitoh, Katsuyuki,Nakano, Masakazu,Suenaga, Yoshihito,Mukaiyama, Teruaki
, p. 621 - 630 (2000)
Carboxamides are prepared in high yields by dehydration condensation between nearly equimolar amounts of free carboxylic acids and amines both of which involve secondary or tertiary alkyl substituted ones with O,O′-di(2-pyridyl) thiocarbonate, a coupling reagent, in the presence of a catalytic amount of 4-(dimethylamino)pyridine.
