172691-30-4

Upstream product

• 172691-24-6 (3S,4R,5S)-tert-butyl-3,7-(bis-tert-butyldiphenylsilyloxy)-4,5-epoxyheptanoate 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 410091-39-3 (3S,4S,5R)-3-(tert-butyldiphenylsilyloxy)-5-[2'-(tert-butyldiphenylsilyloxy)-1'-ethyl]-4-hydroxy-δ-lactone 
• 172691-20-2 (3S,4S,5S)-tert-butyl 3-(3-(2-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)ethyl)(2-oxiranyl))-3-hydroxypropanoate 

Relevant academic research and scientific papers

Stereochemistry control in the lewis acid mediated lactonization reaction of γ,δ-epoxy-β-silyloxy esters

ZnCI2-triggered lactonization reactions of γ,δ-epoxy-β-silyloxy esters with remote alkoxy groups (CH2)nOR (n = 2, 3), producing five- and/or six-membered ring lactones, have been investigated. Under such conditions, the re

Synthesis of 2'-deoxynucleosides substituted in C-5'

Stereocontrolled lactonisation of γ,δ-epoxy β-hydroxyesters provides, after reduction, 2-deoxysugars in pyrano or furano form. After appropriate protection of the hydroxyl functions, these sugars can be converted to various 2'-deoxynucleosides with different configuration of the sugar moiety and an extra functionalisation at C-5.