17274-68-9

Usage

Uses

Used in Pharmaceutical Industry:
5-Bromo-3-[2-(1-pyrrolidinyl)ethyl]-1H-indole is used as a potential pharmaceutical compound for its possible therapeutic applications. The presence of bromine and nitrogen atoms in its structure may allow for the development of new drugs or drug candidates, particularly in the areas of medicinal chemistry and drug discovery.
Used in Chemical Industry:
5-Bromo-3-[2-(1-pyrrolidinyl)ethyl]-1H-indole is used as a chemical intermediate or building block in the synthesis of other compounds. Its unique structure may enable the creation of new chemical entities with specific properties, which could be valuable in various chemical processes and applications.
Used in Research and Development:
5-Bromo-3-[2-(1-pyrrolidinyl)ethyl]-1H-indole is used as a research compound for studying its chemical and physical properties, as well as its potential interactions with other molecules. This research could lead to a better understanding of the compound's behavior and its possible applications in various fields.
Note: The specific applications and uses mentioned above are speculative, as the provided materials do not contain detailed information on the exact applications of 5-Bromo-3-[2-(1-pyrrolidinyl)ethyl]-1H-indole. Further research and studies are necessary to determine its potential uses and effects.

InChI:InChI=1/C14H17BrN2/c15-12-3-4-14-13(9-12)11(10-16-14)5-8-17-6-1-2-7-17/h3-4,9-10,16H,1-2,5-8H2

Upstream product

• 199658-92-9 1-(5-bromo-1H-indol-3-yl)-2-pyrrolidin-1-yl-ethane-1,2-dione 
• 10075-50-0 5-bromo-1H-indole 
• 63843-81-2 2-(5-bromo-1H-indol-3-yl)-2-oxoacetyl chloride 

Downstream Products

• 208464-52-2 5-(1-hydroxycyclohex-1-yl)-3-(2-pyrrolidinylethyl)-1H-indole 
• 208464-44-2 5-bromo-3-(2-pyrrolidinylethyl)-1-benzoylindole 
• 208464-79-3 C₂₆H₂₈N₂O₂ 
• 208464-61-3 5-(cyclohex-1-en-1-yl)-3-(2-pyrrolidinylethyl)-1H-indole 
• 208464-69-1 5-Cyclohexyl-3-(2-pyrrolidinylethyl)-1H-indole 
• 208464-62-4 5-(1-aza-1-benzylcyclohex-3-en-4-yl)-3-(2-pyrrolidinylethyl)-1H-indole 

Relevant academic research and scientific papers

3-(2-Pyrrolidin-1-ylethyl)-5-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives as high affinity human 5-HT1B/1D ligands

A series of 3-(2-pyrrolidin-1-ylethyl)-5-(1,2,3,6-tetrahydropyridin-4-yl)- 1H-indole derivatives (2) has been prepared using parallel synthesis techniques, and their structure-activity relationships studied. High affinity human 5-HT1B/1D (h5-HT1B/1D) ligands have been identified.

5-CYCLO INDOLE COMPOUNDS AS 5-HT1D RECEPTOR LIGANDS

Described herein are compounds selective for a 5-HT1D-like receptor, which have general formula (I), wherein A is selected from a six-membered, non-aromatic, optionally substituted carbocycle and a six-membered, non-aromatic, optionally substituted heterocycle having one or two heteroatoms selected from O, S, SO, SO2 and NR; R is selected from H and OH; n is 0 or 1 as permitted by chemical structure; R is selected from CRRCH2NRR or a group of formula (II), (III) or (IV); R is selected from H and benzoyl; R is selected from H, loweralkyl, benzyl, loweralkylcarbonyl, loweralkylaminocarbonyl; loweralkylaminothiocarbonyl, loweralkanoyl, loweralkylaminoimide and loweralkoxy-substituted loweralkylene; R and R are independently selected from H, loweralkoxy and hydroxy; R and R are independently selected from H and loweralkyl or R and R form an alkylene bridge which, together with the nitrogen atom to which they are attached, creates an optionally substituted 3- to 6-membered ring; ----- denotes a single or double bond; and R, R and R are independently selected from H and loweralkyl. Also described is the use of these compounds as pharmaceuticals to treat indications where stimulation of a 5-HT1D-like receptor is implicated, such as migraine.