17277-23-5Relevant academic research and scientific papers
Synthesis, characterization and antibacterial activity of the thioether linked 1,2,3-triazoles
Kaushik, Chander P.,Sangwan, Jyoti
supporting information, p. 3403 - 3415 (2021/09/13)
A green synthetic approach for the expedite construction of thirty six thioether linked 1,2,3-triazoles was carried out using Cellulose supported CuI nanoparticles in water. The structure of synthesized triazoles was explicated by spectroscopic techniques
Photochemical Doyle-Kirmse Reaction: A Route to Allenes
Or?owska, Katarzyna,Rybicka-Jasińska, Katarzyna,Krajewski, Piotr,Gryko, Dorota
supporting information, p. 1018 - 1021 (2020/01/31)
This Letter describes the metal-free, blue-light-induced [2,3]-sigmatropic rearrangement of sulfonium ylides generated from donor/acceptor diazoalkanes and propargyl sulfides. The reaction furnishes highly functionalized allenes from a broad range of starting materials in decent yield. Mechanistic experiments supported by the literature data suggest singlet carbenes as intermediates in this reaction.
Gold-Catalyzed Oxidative Hydrative Alkenylations of Propargyl Aryl Thioethers with Quinoline N-Oxides Involving a 1,3-Sulfur Migration
Wagh, Sachin Bhausaheb,Singh, Rahulkumar Rajmani,Sahani, Rajkumar Lalji,Liu, Rai-Shung
supporting information, p. 2755 - 2758 (2019/04/30)
This work reports gold-catalyzed oxidative alkenylations of quinoline N-oxides with propargyl aryl thioethers to afford 3-hydroxy-1-alkylidenephenylthiopropan-2-one via a 1,3-sulfur group migration. The mechanism of this reaction is postulated to involve
Convenient synthesis, antimalarial and antimicrobial potential of thioethereal 1,4-disubstituted 1,2,3-triazoles with ester functionality
Kaushik,Pahwa, Ashima
, p. 458 - 469 (2017/10/13)
This paper elicits the synthesis of twenty five 1,4-disubstituted 1,2,3-triazole analogs (5a–5y) comprising thioether and ester linkages from aryl(prop-2-yn-1-yl)sulfanes and benzyl 2-azidoacetates employing Cu(I) catalyzed Huisgen 1,3-dipolar cycloaddition. Structures of synthesized compounds were elucidated by spectroscopic techniques like FTIR, 1H NMR, 13C NMR, and HRMS. Newly synthesized compounds were screened for in vitro antimalarial evaluation against P. falciparum strain and microbicidal potential against B. subtilis, S. epidermidis, E. coli, P. aeruginosa, C. albicans, and A. niger. Some of synthesized triazoles displayed moderate antimalarial activity against tested strain, while, the compounds 5i and 5n were found to exhibit significant inhibitory activity against most of the tested microbial strains.
A two-step synthesis of α-keto vinyl carbinols from ketones
Debien, Laurent,Zard, Samir Z.
supporting information, p. 6066 - 6069 (2014/01/06)
Conjugate addition of lithium enolates onto terminal alkynyl- and allenyl-sulfoxides furnishes the corresponding allylic sulfoxides. The latter readily undergo a Mislow-Braverman-Evans rearrangement to yield the targeted α-keto vinyl carbinols. This two-s
Intermolecular and intramolecular pauson-khand reactions of functionalized Allenes
Gonzalez-Gomez, Alvaro,Anorbe, Loreto,Poblador, Amalia,Dominguez, Gema,Perez-Castells, Javier
supporting information; experimental part, p. 1370 - 1377 (2009/04/11)
Pauson-Khand reactions of functionalized allenes with different alkynes give cyclopentenones with generally high regio-and stereoselectivities. The allenes react through their external double bonds, giving cyclopentenones with exocyclic double bond at their β positions and predominantly with E stereochemistry. Some intramolecular reactions with allenynes connected through aromatic rings are described. These give the corresponding heterocycles with moderate to good yields. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
Mass Spectral Rearrangements of 3-Arylsulphonyl-2-arylthiopropenes and N-(4'-Arylsulphonyl-2'-butynyl)-N-(4"-arylthio-2"-butynyl)anilines
Glaspy, P. E.,Hancock, R. A.,Thyagarajan, B. S.
, p. 281 - 287 (2007/10/02)
Under electron impact the title compounds undergo skeletal rearrangement in the addition to the anticipated modes of cleavage.The 3-arylsulphonyl-2-arylthiopropenes readily eliminate sulphur dioxide.Other modes of fragmentation include rearrangement to a
