17281-87-7Relevant academic research and scientific papers
Iodine-promoted synthesis of acylindolizine derivatives from acetylenecarboxylates and pyridinium, isoquinolinium, or quinolinium ylides
Liu, Juanjuan,Yan, Peiyun,Li, Yan,Zhou, Zhengquan,Ye, Weijian,Yao, Juan,Wang, Cunde
, p. 617 - 625 (2014/04/03)
An iodine-promoted synthesis of acylindolizinecarboxylates via 1,3-dipolar cycloaddition of nitrogen ylides with acetylenecarboxylates and subsequent aromatization for the generation of a wide range of structurally interesting, pharmacologically and photoelectrically significant compounds is reported. Only readily available materials, mild conditions, and operationally trivial reaction protocols were required. Graphical abstract: [Figure not available: see fulltext.]
Amberlite-IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: Antibacterial and antifungal evaluation of the products
Hazra, Abhijit,Mondal, Shyamal,Maity, Arindam,Naskar, Subhendu,Saha, Pritam,Paira, Rupankar,Sahu, Krishnendu B.,Paira, Priyankar,Ghosh, Soma,Sinha, Chandrima,Samanta, Amalesh,Banerjee, Sukdeb,Mondal, Nirup B.
experimental part, p. 2132 - 2140 (2011/06/21)
A number of indolizines and pyrrolo[1,2-a]quinolines/isoquinolines were prepared from phenacyl pyridinium, quinolinium and isoquinolinium salts derived fromthe reaction of the heterocycles with 2-bromo acetophenone with alkynes and alkenes using amberlite-IRA-402 (OH) ion exchange resin as the base. Antibacterial and antifungal studies were carried out against thirteen bacterial and four fungal strains, which revealed that three derivatives (4a, 4b, 7a) out of fifteen are effective against all the thirteen strains and one derivative, 10, showed dual antibactericidal and antifungal efficacy.
Efficient synthesis of pyrrolo[2,1-a]isoquinoline and pyrrolo[1,2-a] quinoline derivatives in aqueous media
Kianmehr, Ebrahim,Estiri, Hamid,Bahreman, Azadeh
experimental part, p. 1203 - 1207 (2010/03/04)
(Chemical Equation Presented) A one-pot procedure for the synthesis of pyrrolo[2,1-a]isoquinolines and pyrrolo[1,2-a]quinolines in good to excellent yields has been reported, using quinoline or isoquinoline, phenacylbromide derivatives and activated alkyn
Studies on 1,3-Dipolar Cycloaddition Reactions of Some Cycloimmonium Ylides
Tewari, Ram S.,Dubey, Ajay K.,Misra, Naresh K.
, p. 101 - 103 (2007/10/02)
1,3-Dipolar cycloaddition reactions of zwitterionic quinolinium and isoquinolinium ylides, generated in situ from their respective precursors, with acetylenic dipolarophiles led to the formation of benzoindolizine derivatives .The reaction presumably proc
