17286-67-8

Upstream product

• 635-84-7 4-(chloroacetyl)biphenyl 
• 95-54-5 1,2-diamino-benzene 
• 92-91-1 biphenyl-4-acetaldehyde 
• 29079-00-3 4-ethynyl-1,1'-biphenyl 
• 37166-61-3 1-([1,1′-biphenyl]-4-yl)-2-hydroxyethanone 
• 135-73-9 2-Bromo-4'-phenylacetophenone 
• 40240-62-8 1-(2-([1,1'-biphenyl]-4-yl)-2-oxoethyl)pyridin-1-ium bromide 
• 4974-58-7 4-biphenylglyoxal 

Downstream Products

• 1444302-46-8 2-(3-fluorobiphenyl-4-yl)quinoxaline 
• 1420295-61-9 2-(biphenyl-4-yl)-3-(dimethoxymethyl)quinoxaline 
• 1327154-18-6 2-([1,1'-biphenyl]-4-yl)-1,2,3,4-tetrahydroquinoxaline 
• 1262801-90-0 2-(4-phenyl-2-nitrophenyl)quinoxaline 

Relevant academic research and scientific papers

Silica supported dodecatungstophosphoric acid (DTP/SiO2): An efficient and recyclable heterogeneous catalyst for rapid synthesis of quinoxalines

A facile synthesis of quinoxalines by the cyclocondensation of substituted phenacyl bromides with o-pheneylenediamines using silica-supported dodecatungstophosphoric acid (DTP/SiO2) as a recyclable heterogeneous catalyst is unveiled in this res

Direct Aerobic Oxidative Reactions of 2-Hydroxyacetophenones

Valuable and direct aerobic oxidation reactions of 2-hydroxyacetophenones were explored. The concept was based on the in situ treatment of small quantities of aerobically formed α-keto aldehydes that drove the reactions to the corresponding products. This new strategy was applied for a variety of oxidative reactions of 2-hydroxyacetophenones, and valuable products such as phthalides, quinoxalines, and α-keto amides were obtained in good to high yields.

Expeditious one-pot multicomponent microwave-assisted green synthesis of substituted 2-phenyl Quinoxaline and 7-bromo-3-(4-ethylphenyl) pyrido[2,3-b]pyrazine in water–PEG and water–ethanol

An eco-friendly, expeditious one-pot multicomponent synthesis of substituted 2-phenyl quinoxaline and 7-bromo-3-(4-ethylphenyl) pyrido[2,3-b]pyrazine 4a–k in water–ethanol from easily available starting materials as acetophenone 1, succinamide 2, aromatic

One-step approach for the synthesis of functionalized quinoxalines mediated by T3P-DMSO or T3P: Via a tandem oxidation-condensation or condensation reaction

An easy and efficient propylphosphonic anhydride (T3P)-DMSO or T3P mediated oxidation-condensation or condensation reaction for the synthesis of quinoxalines derived from the interaction of different arrays of condensing partners with ortho-phenylene diamines (o-PDs) under simple and mild reaction conditions in one step has been reported for the first time.

N-Bromosuccinimide-Mediated Synthesis of Substituted Quinoxalines

An efficient and simple N-bromosuccinimide-mediated two-step synthesis of substituted quinoxalines from 1,2-diarylacetylenes and 1,2-diaminobenzenes in boiling AcOH, during a one-pot procedure has been developed. All the structures of the substituted quinoxalines were confirmed, some by single-crystal X-ray crystallography. Possible reaction pathways were discussed, and some data were matched with the previous work.

I2/Cu-mediated self-sorting domino reaction of aryl β-ketoesters into symmetrical 2-carboalkoxy-1,4-enediones: Application to synthesis of pyrazine, β-carboline and quinoxalines

A self-sorting domino reaction of aryl β-ketoesters into symmetrical 1,4-enediones is reported by an I2/Cu system. The reaction proceeds through tandem iodination, self-dimerization and Krapcho dealkoxycarbonylation in one pot under open air condition. Further, 1,4-enediones were successfully employed for the synthesis of bioactive pyrazine, β-carboline and quinoxalines via aza-Michael addition, intramolecular cyclization and C-C bond cleavage of 1,3-dicarbonyl unit under mild reaction condition. This journal is

Catalyst-free synthesis of quinoxalines

Quinoxalines are a class of important heterocycles, so to explore a facile and practical new synthetic method is always demanded. We have developed a new catalyst-free domino synthesis of quinoxalines from phenacyl halides and 1,2-diaminoarenes. Phenacyl

Gold-catalyzed synthesis of glyoxals by oxidation of terminal alkynes: One-pot synthesis of quinoxalines

From terminal alkynes to glyoxals: Terminal alkynes can be oxidized under mild conditions by the use of an N-oxide in the presence of a gold catalyst. The intermediate glyoxal derivatives can be transferred in a one-pot procedure to substituted quinoxalines (see scheme). Copyright

Logic design and synthesis of quinoxalines via the integration of iodination/oxidation/cyclization sequences from ketones and 1,2-diamines

A novel protocol for the synthesis of quinoxalines has been developed from simple ketones and 1,2-diamines. This process underwent a logic approach to bis-substituted quinoxalines via a consecutive iodination/Kornblum oxidation/cyclization in the presence of I2/CuO/DMSO and to mono-substituted quinoxalines via an iodination/cyclization/aromatization in the presence of I2/CuO/K3PO4·3H 2O.

Biomimetic synthesis of quinoxalines in water

Various quinoxalines have been synthesized for the first time in the presence of β-cyclodextrin in water. Biomimetic catalysis of β-cyclodextrin is explained by using 1H NMR spectroscopy.