172924-74-2

Upstream product

• 172788-55-5 Methyl <(S)-5-(benzyloxy)-2,6,6-trimethylcyclohex-1-en-1-yl>-3-oxopentanoate 
• 106540-32-3 (3S)-3-t-butyldimethylsilyloxy-2,2,6-trimethylcyclohexanone 
• 172788-52-2 3,3-(Ethylenedioxy)-1-<(S)-5-hydroxy-2,6,6-trimethylcyclohexenyl>butane 
• 172788-53-3 1-<(S)-5-(Benzyloxy)-2,6,6-trimethylcyclohex-1-en-1-yl>-3,3-(ethylenedioxy)butane 

Downstream Products

• 534600-69-6 3-[(E)-5-Benzenesulfonyl-3-methyl-5-((4aR,8aR)-2,5,5,8a-tetramethyl-3,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl)-pent-2-enyl]-4-benzyloxy-benzoic acid benzyl ester 
• 534600-70-9 4-benzyloxy-3-{(2'E)-3'-methyl-5'-[(4aR,8aR)-2,5,5,8a-tetramethyl-3,4,4a,5,6,7,8,8a-octahydronaphthyl]-2'-pentenyl}benzoic acid 
• 534600-65-2 (4aR,8aR)-8-benzenesulfonylmethyl-4,4,7,8a-tetramethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalene 

Relevant academic research and scientific papers

Synthesis and absolute configuration of (-)-subersic acid, a sponge-derived, terpenoidal inhibitor of human 15-lipoxygenase

(-)-Subersic acid (1), a new derivative of p-hydroxybenzoic acid in which the m-position is substituted with a bicyclic diterpenoid was synthesized from (S)-3-hydroxy-2,2-dimethylcyclohexanone and p-hydroxybenzoic acid. The stereochemistry of this sponge-

Diterpenoid Total Synthesis, XXXI. Synthesis and Absolute Configuration of (-)-Stypoldione, a Metabolite of Stypopodium zonale

(S)-3-Hydroxy-2,2-dimethylcyclohexanone (2) was converted to (-)-stypoldione (1), the ichthyotoxic and cytotoxic metabolite of the brown alga Stypopodium zonale.The present synthesis established the absolute configuration of (-)-stypoldione as depicted in