172950-34-4

Basic information

• Product Name: N-[(2R,3R,4R,5S,6R)-5-((2S,3R,4S,5R,6R)-4-Azido-3,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-4-benzyloxy-6-benzyloxymethyl-2-methoxy-tetrahydro-pyran-3-yl]-acetamide
• CAS NO: 172950-34-4
• Molecular Weight: 602.642
• Mol File: 172950-34-4.mol

Chemical Properties

• CAS DataBase Reference: N-[(2R,3R,4R,5S,6R)-5-((2S,3R,4S,5R,6R)-4-Azido-3,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-4-benzyloxy-6-benzyloxymethyl-2-methoxy-tetrahydro-pyran-3-yl]-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(2R,3R,4R,5S,6R)-5-((2S,3R,4S,5R,6R)-4-Azido-3,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-4-benzyloxy-6-benzyloxymethyl-2-methoxy-tetrahydro-pyran-3-yl]-acetamide(172950-34-4)
• EPA Substance Registry System: N-[(2R,3R,4R,5S,6R)-5-((2S,3R,4S,5R,6R)-4-Azido-3,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-4-benzyloxy-6-benzyloxymethyl-2-methoxy-tetrahydro-pyran-3-yl]-acetamide(172950-34-4)

Safety Data

• Hazardous Substances Data: 172950-34-4(Hazardous Substances Data)

Upstream product

• 172950-32-2 methyl 2,4,6-tri-O-acetyl-3-azido-3-deoxy-β-D-galactopyranosyl-(1[*]4)-3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside 
• 155301-09-0 2,4,6-tri-O-acetyl-3-azido-3-deoxy-β-D-galactopyranosyl bromide 
• 97242-79-0 methyl 3,6-di-O-benzyl-2-deoxy-2-N-phthalimido-β-D-glucopyranoside 
• 108-24-7 acetic anhydride 
• 172950-33-3 (2S,3R,4S,5R,6R)-2-((2R,3S,4R,5R,6R)-5-Amino-4-benzyloxy-2-benzyloxymethyl-6-methoxy-tetrahydro-pyran-3-yloxy)-4-azido-6-hydroxymethyl-tetrahydro-pyran-3,5-diol 

Relevant articles and documents

Methyl 3-amino-3-deoxy-β-D-galactopyranosyl-(1 → 4)-2-acetamido-2-deoxy-β-D-glucopyranoside: An inhibitor of UDP-D-galactose: β-D-galactopyranosyl-[1 → 4)-2-acetamido-2-deoxy-D-glucose (1 → 3)-α-D-galactopyranosyltransferase

UDP-D-galactose: β-D-galactopyranosyl-(1 → 4)-2-acetamido-2-deoxy-D-glucose α-(1 → 3)-D-galactopyranosyltransferase [E.C. 2.4.1.151] transfers D-galactosyl-residues from the sugar nucleotide with retention of configuration. We report here that synthetic methyl 3'-amino-3'-deoxy-N-acetyllactosaminide (9), where the hydroxyl group normally undergoing galactosylation has been replaced by amino group, is an inhibitor for this enzyme with K(i) = 104 μM. The mode of inhibition is not competitive, but appears to be specific, since other glycosyltransferases were not affected by 9.