172970-89-7

Upstream product

• 401519-23-1 3-(3-cyclopentyloxy-4-methoxyphenyl)-2,4-bis(ethoxycarbonyl)-5-hydroxy-5-methylcyclohexan-1-one 
• 1427298-73-4 2,4-diacetyl-3-(3-cyclopentyloxy-4-methoxyphenyl)pentanedioic acid diethyl ester 
• 67387-76-2 3-cyclopentyloxy-4-methoxybenzylaldehyde 

Downstream Products

• 160818-95-1 4-(3-cyclopentyloxy-4-methoxyphenyl)piperidin-2,6-dione 
• 1427298-74-5 4-(3-cyclopentyloxy-4-methoxyphenyl)dihydropyran-2,6-dione 
• 1427298-79-0 (S)-3-(3-cyclopentyloxy-4-methoxyphenyl)pentanedioic acid monocinnamyl ester 
• 1427298-77-8 (R)-3-(3-cyclopentyloxy-4-methoxyphenyl)pentanedioic acid monocinnamyl ester 
• 1427298-75-6 (R)-3-(3-cyclopentyloxy-4-methoxyphenyl)pentanedioic acid monobenzyl ester 
• 85416-75-7 (R)-4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one 
• 85416-73-5 (S)-rolipram 
• 1427298-78-9 (S)-3-(3-cyclopentyloxy-4-methoxyphenyl)pentanedioic acid monobenzyl ester 

Relevant academic research and scientific papers

A simple enantioselective route toward (R)- and (S)-Rolipram via anhydride desymmetrization

A highly enantioselective metal-free synthesis of both enantiomers of Rolipram is reported. The key stereoinductive step is a cinchona alkaloid catalyzed opening of a cyclic anhydride prepared from isovanillin, where both enantiomers are available using t

Piperidine derivatives and drugs containing these derivatives as active ingredient

Piperidine derivatives represented by formula (I) or nontoxic salts thereof (wherein symbols are defined in the description): Since the compound represented by formula (I) has a PDE4 inhibitory activity, it is useful for preventing and/or treating inflamm