173064-87-4

Basic information

• Product Name: 5H-Cyclopenta[b]pyridin-5-one,6,7-dihydro-4-methyl-(9CI)
• Synonyms: 5H-Cyclopenta[b]pyridin-5-one,6,7-dihydro-4-methyl-(9CI)
• CAS NO: 173064-87-4
• Molecular Formula: C9H9NO
• Molecular Weight: 147.17386
• Product Categories: PYRIDINE
• Mol File: 173064-87-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5H-Cyclopenta[b]pyridin-5-one,6,7-dihydro-4-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5H-Cyclopenta[b]pyridin-5-one,6,7-dihydro-4-methyl-(9CI)(173064-87-4)
• EPA Substance Registry System: 5H-Cyclopenta[b]pyridin-5-one,6,7-dihydro-4-methyl-(9CI)(173064-87-4)

Safety Data

• Hazardous Substances Data: 173064-87-4(Hazardous Substances Data)

Upstream product

• 5436-21-5 acetylacetaldehyde dimethyl acetal 
• 28566-12-3 3-amino-cyclopent-2-en-1-one 
• 173064-88-5 trans-1,3-Bis-<1-aminocyclopent-1-en-3-onyl-(2)>-but-1-en 

Relevant articles and documents

A regioselective synthesis of 4-methyl-1-pyrindan-5-one

The enamine 7 reacts with crotonic aldehyde in the presence of p-toluenesulphonic acid via the intermediate 8 to yield regioselectively the unknown title compound 9. In alkaline medium, 9 is also formed from 7 and acetylacetaldehyde dimethyl acetal as well as small amounts of 11 and 12; under acidic conditions, however, mixtures of the regioisomers 9/9a are obtained in poor yield. 9a can be separated by fractional crystallisation of the hydrochlorides. Corresponding to 7 the homologous enamine 13 and acetylacetaldehyde acetal by alkaline catalysis gives the 4-methyltetrahydroquinolinone 1, respectively. Improved experimental details for an efficient preparation of the starting compounds 3 and 4 are given.