173094-49-0Relevant articles and documents
Synthese d'oxazolines insaturees isomeres a partir d'aminoalcools chiraux en vue du greffage sur silice
Leveque, Hubert,Malhiac, Catherine,Speybrouck, David,Combret, Yvette,Guerpin, Valerie,Combret, Jean-Claude
, p. 801 - 807 (2007/10/02)
Synthesis of unsaturated oxazoline isomers from chiral amino alcohols for bonding to silica.In order to study their enantioselective ability, four chiral unsaturated oxazoline isomers were synthesized from (1S,2S)-2-amino-1-phenylpropane-1,3-diol and (2S,3R)-2-amino-3-hydroxybutanoic acid (S-threonine).A terminal double bond was introduced on these structures in order to be able to graft them onto silica and access chiral stationary phases for chromatography. - Keywords: chiral unsaturated oxazoline; heterocyclization; selective reaction; grafted silica