173106-39-3

Basic information

• Product Name: 11-{[(3beta)-29-[(4-fluorophenyl)sulfanyl]-3-hydroxy-28-oxolup-20(30)-en-28-yl]amino}undecanoic acid
• CAS NO: 173106-39-3
• Molecular Formula: C₄₇H₇₂FNO₄S
• Molecular Weight: 766.1423
• Mol File: 173106-39-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 826.5°C at 760 mmHg
• Flash Point: 453.7°C
• Density: 1.13g/cm³
• Vapor Pressure: 6.16E-29mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: 11-{[(3beta)-29-[(4-fluorophenyl)sulfanyl]-3-hydroxy-28-oxolup-20(30)-en-28-yl]amino}undecanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 11-{[(3beta)-29-[(4-fluorophenyl)sulfanyl]-3-hydroxy-28-oxolup-20(30)-en-28-yl]amino}undecanoic acid(173106-39-3)
• EPA Substance Registry System: 11-{[(3beta)-29-[(4-fluorophenyl)sulfanyl]-3-hydroxy-28-oxolup-20(30)-en-28-yl]amino}undecanoic acid(173106-39-3)

Safety Data

• Hazardous Substances Data: 173106-39-3(Hazardous Substances Data)

Upstream product

• 150840-96-3 11-[((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-Acetoxy-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-icosahydro-cyclopenta[a]chrysene-3a-carbonyl)-amino]-undecanoic acid methyl ester 
• 59868-82-5 3-O-acetylbetulinic acid chloride 
• 10376-50-8 3-O-acetylbetulinic acid 
• 371-42-6 4-Fluorothiophenol 
• 173106-33-7 11-({(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bS)-9-Acetoxy-1-[1-(4-fluoro-phenylsulfanylmethyl)-vinyl]-5a,5b,8,8,11a-pentamethyl-icosahydro-cyclopenta[a]chrysene-3a-carbonyl}-amino)-undecanoic acid methyl ester 
• 173106-29-1 11-{[(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bS)-9-Acetoxy-1-(1-bromomethyl-vinyl)-5a,5b,8,8,11a-pentamethyl-icosahydro-cyclopenta[a]chrysene-3a-carbonyl]-amino}-undecanoic acid methyl ester 

Relevant articles and documents

Betulinic acid derivatives: A new class of human immunodeficiency virus type 1 specific inhibitors with a new mode of action

A series of ω-undecanoic amides of lup-20(29)-en-28-oic acid derivatives were synthesized and evaluated for activity in CEM 4 and MT-4 cell cultures against human immunodeficiency virus type 1 (HIV-1) strain III(B)/LAI. The potent HIV inhibitors which emerged, compounds 5a, 16a, and 17b, were all derivatives of betulinic acid (3β-hydroxylup-20(29)-en-28-oic acid). No activity was found against HIV-2 strain ROD. Compound 5a showed no inhibition of HIV-1 reverse transcriptase activity with poly(C)·oligo(dG) as template/primer, nor did it inhibit HIV-1 protease. Additional mechanistic studies revealed that this class of compounds interfere with HIV-1 entry in the cells at a postbinding step.