173153-66-7Relevant academic research and scientific papers
Mono- and bicyclic DNA gyrase inhibitors
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, (2008/06/13)
The present invention relates to a compound of the formula STR1 wherein X1, R1, R2, OP, R3, R4, R5, R6, and R0 are as described herein, and their pharmaceutically acceptable salts thereof carrying an acidic and/or basic substituent. The compound of formula I as well as their pharmaceutically acceptable salts inhibit DNA gyrase activity in bacteria and possess antibiotic, especially antibacterial activity against microorganisms and can be used in the control or prevention of infectious diseases.
