173171-08-9

Upstream product

• 110-89-4 piperidine 
• 354153-47-2 (+/-)-1-(2,4,6-trimethyl-phenyl)-ethane-1,2-diol 
• 139016-19-6 (R)-1-(2,4,6-trimethylphenyl)-1,2-ethanediol 
• 769-25-5 2,4,6-trimethylstyrene 
• 50447-68-2 (R)-2-(2,4,6-trimethylphenyl)oxirane 

Downstream Products

• 1026982-52-4 Methanesulfonic acid (R)-2-piperidin-1-yl-1-(2,4,6-trimethyl-phenyl)-ethyl ester 

Relevant academic research and scientific papers

Acid-Assisted Ru-Catalyzed Enantioselective Amination of 1,2-Diols through Borrowing Hydrogen

Here, we present a highly enantioselective synthesis of 1,2-amino alcohols from readily available racemic 1,2-diols through a borrowing hydrogen process. An intriguing acid effect was discovered for this Ru-catalyzed amination reaction, which led to a sig