173199-87-6Relevant academic research and scientific papers
Stereoselective transformation of pyrazinones into substituted analogues of cis-5-amino-6-oxo-2-piperidinemethanol and cis-5-amino-2-piperidinemethanol
Rogiers, Joeri,De Borggraeve, Wim M.,Toppet, Suzanne M.,Compernolle, Frans,Hoornaert, Georges J.
, p. 5047 - 5054 (2007/10/03)
Various analogues of cis-5-amino-6-oxo-2-piperidinemethanol and cis-5-amino-2-piperidinemethanol have been prepared via Diels-Alder reaction of substituted pyrazinones with ethene followed by acid methanolysis of the bridged lactam adducts. Further reduct
Intramolecular Diels-Alder Reactions of 2(1H)-Pyrazinones: Synthesis of New Furo/Pyrano-pyridinones and -pyridines
Buysens, Kris J.,Vandenberghe, Didier M.,Toppet, Suzanne M.,Hoornaert, Georges J.
, p. 12463 - 12478 (2007/10/02)
2(1H)-Pyrazinones 2-5 with in 3-position either a 3- or 4-alkynyloxy side chain and 2(1H)-pyrazinones 9-10 carrying the corresponding 2- or 3-alkynyloxy(m)ethyl substituent are shown to undergo intramolecular Diels-Alder reaction.The formation of either f
