173200-35-6Relevant articles and documents
Synthesis and fungicidal activity of 3,5-dichloropyrazin-2(1H)-one derivatives
Francois, Isabelle E.J.A.,Cammue, Bruno P.A.,Bresseleers, Sara,Fleuren, Hein,Hoornaert, Georges,Mehta, Vaibhav P.,Modha, Sachin G.,Van der Eycken, Erik V.,Thevissen, Karin
supporting information; experimental part, p. 4064 - 4066 (2010/03/25)
We synthesized a family of 3,5-dichloropyrazin-2(1H)-one derivatives and assessed their in vitro fungicidal activity against Candida albicans. Compounds 11 and 20 were most active against C. albicans and induced accumulation of reactive oxygen species in
Design and synthesis of novel type VI-like β-turn mimetics. Diversity at the i+1 and the i+2 position
De Borggraeve, Wim M.,Verbist, Bie M.P.,Rombouts, Frederik J.R.,Pawar, Vijaykumar G.,Smets, Wim J.,Kamoune, Laila,Alen, Jo,Van Der Eycken, Erik V.,Compernolle, Frans,Hoornaert, Georges J.
, p. 11597 - 11612 (2007/10/03)
In this paper, a synthetic approach for functionalised 5-aminopiperidinone- 2-carboxylate (APC) systems as non-pro cis-peptide bond containing external β-turn mimics is presented. The scope and limitations of the synthetic method are discussed and the pot