17321-35-6

Basic information

• Product Name: 3-Iodo-6-methoxypyridazine
• Synonyms: 3-Iodo-6-methoxypyridazine;3-Iodo-6-methoxy-1,2-diazine;Pyridazine,3-iodo-6-methoxy-
• CAS NO: 17321-35-6
• Molecular Formula: C₅H₅IN₂O
• Molecular Weight: 236.01
• Product Categories: Halides;Pyrazines, Pyrimidines & Pyridazines
• Mol File: 17321-35-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 334°Cat760mmHg
• Flash Point: 155.8°C
• Appearance: /
• Density: 1.935g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.605
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 3-Iodo-6-methoxypyridazine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Iodo-6-methoxypyridazine(17321-35-6)
• EPA Substance Registry System: 3-Iodo-6-methoxypyridazine(17321-35-6)

Safety Data

• Hazardous Substances Data: 17321-35-6(Hazardous Substances Data)

Usage

General Description

3-Iodo-6-methoxypyridazine is a chemical compound with the molecular formula C5H5IN2O. It is a halogenated pyridazine derivative that consists of a pyridazine core with a methoxy group at the 6-position and an iodine atom at the 3-position. 3-Iodo-6-methoxypyridazine is commonly used as a building block in organic synthesis and medicinal chemistry research. It has demonstrated potential pharmacological activities, particularly in the field of anti-inflammatory and antimicrobial agents. 3-Iodo-6-methoxypyridazine is a valuable tool for the development of novel pharmaceuticals and biologically active compounds.

InChI:InChI=1/C5H5IN2O/c1-9-5-3-2-4(6)7-8-5/h2-3H,1H3

Upstream product

• 20698-04-8 3,6-diiodopyridazine 
• 67-56-1 methanol 
• 124-41-4 sodium methylate 

Downstream Products

• 68321-53-9 3-(phenylethynyl)-6-methoxypyridazine 
• 4578-42-1 3-methoxy-6-phenylpyridazine 
• 99984-42-6 6-methoxy-3-(phenylsulfanyl)pyridazine 
• 173088-61-4 (E)-p-nitrophenyl 3-(2-methoxy-5-pyridazinyl)acrylate 
• 1019331-16-8 3-ethynyl-6-methoxypyridazine 

Relevant articles and documents

First synthesis of novel 3,3′-bipyridazine derivatives as new potent antihepatocellular carcinoma agents

Hepatocellular carcinoma is one of the most common kind of cancers in clinical, and its clinical treatment is quite difficult. The latest research suggests that pyridazinone with a novel molecular skeleton shows excellent activity against hepatocellular c

Synthesis of some 3,6-disubstituted pyridazines

Some novel 3-halo-6-(4-substituted-phenoxy)pyridazines and 3,6-di-(4- substituted-phenoxy)pyridazines were synthesized from 3,6-dichloropyridazine or 3,6-diiodopyridazine. 3,6-Diiodopyridazine was prepared from 3,6- dichloropyridazine using hydriodic acid/iodine monochloride.

Synthesis of unsymmetrical 3,6-disubstituted pyridazines. A palladium-catalyzed approach from 3-iodopyridazines

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