173260-10-1

Basic information

• Product Name: dimethyl 4-amino-1-[(4-methylphenyl)sulfonyl]-3-(methylsulfanyl)-1H-pyrazolo[3,4-b]pyridine-5,6-dicarboxylate
• Synonyms: dimethyl 4-amino-1-[(4-methylphenyl)sulfonyl]-3-(methylsulfanyl)-1H-pyrazolo[3,4-b]pyridine-5,6-dicarboxylate
• CAS NO: 173260-10-1
• Molecular Formula: C₁₈H₁₈N₄O₆S₂
• Molecular Weight: 450.48872
• Mol File: 173260-10-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: dimethyl 4-amino-1-[(4-methylphenyl)sulfonyl]-3-(methylsulfanyl)-1H-pyrazolo[3,4-b]pyridine-5,6-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 4-amino-1-[(4-methylphenyl)sulfonyl]-3-(methylsulfanyl)-1H-pyrazolo[3,4-b]pyridine-5,6-dicarboxylate(173260-10-1)
• EPA Substance Registry System: dimethyl 4-amino-1-[(4-methylphenyl)sulfonyl]-3-(methylsulfanyl)-1H-pyrazolo[3,4-b]pyridine-5,6-dicarboxylate(173260-10-1)

Safety Data

• Hazardous Substances Data: 173260-10-1(Hazardous Substances Data)

Upstream product

• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 5147-80-8 [Bis(methylthio)methylene]malononitrile 
• 762-42-5 dimethyl acetylenedicarboxylate 

Relevant articles and documents

Synthesis and chemiluminescence of 1,3-disubstituted pyrazolo[4',3':5,6]pyrido[2,3-d]pyridazine-5,8(6H,7H)-diones and related compounds

Reactions of 1,3-disubstituted 5-aminopyrazole 5-aminopyrazole-4-carbonitrile derivatives (3a-o) with dimethyl acetylenedicarboxylate in the presence of potassium carbonate in dimethyl sulfoxide gave the corresponding dimethyl 1,3-disubstituted pyrazolo[3,4-b]pyridine-5,6-dicarboxylates (4a-o) which were allowed to react with excess hydrazine hydrate in ethanol under reflux followed by heating at 250-300°C to give 1,3-disubstituted 4-amino-1H-pyrazolo[4',3':5,6]pyrido[2,3-d]pyridazine-5,8(6H,7H)-dione s (7a-s) in good yields. These tricyclic pyridazine derivatives were evaluated for chemiluminescence. Some were found to be more efficient than luminol in light production. 4-Amino-3-methylsulfonyl-1-phenyl-1H-pyrazolo[4',3':5,6]pyrido[2,3-d]p yridazine-5,8(6H,7H)-dione (7r) showed the greatest chemiluminescence intensity derivatives in the presence of H2O2, peroxidase, in a solution of phosphate buffer pH 8.0.