173277-06-0Relevant academic research and scientific papers
Facile preparation of allyl amines and pyrazoles by hydrazinolysis of 2-ketoaziridines
Chen, Gang,Sasaki, Mikio,Yudin, Andrei K.
, p. 255 - 259 (2007/10/03)
Allyl amines and pyrazoles can be obtained by hydrazinolysis of 2-ketoaziridines. A variety of aziridines, including N-unprotected, N-substituted, as well as bicyclic enamine and aminal type, can be transformed into diversely substituted linear or cyclic products. The hydrazinolysis of homochiral aziridines proceeds without racemization.
A novel two-step preparation of enaminoketones by amination of α,β- unsaturated ketones with methoxyamine
Seko, Shinzo,Tani, Nobuhiro
, p. 8117 - 8120 (2007/10/03)
β-Methoxyaminoketones, derived from the addition of methoxyamine to 1,3-diaryl-2-propen-1-one, underwent base-induced β-elimination to furnish the corresponding enaminoketones in good to moderate yields. The reaction conditions and substituents on the substrates significantly influenced the selectivity in the production of enaminoketone and/or aziridineketone.
Synthesis of 4-phenylpiperidines by tandem Wittig olefination-aza-Wittig rearrangement of 2-benzoylaziridines
Coldham, Iain,Collis, Alan J.,Mould, Roger J.,Rathmell, Richard E.
, p. 2739 - 2746 (2007/10/02)
A number of routes to 2-vinylaziridines are reported.N-Alkylation of a range of 2-benzoyl-3-alkylaziridines with tert-butyl bromoacetate followed by Wittig olefination gave directly a range of 4-phenylpiperidines.The intermediate 2-vinylaziridines rearran
