173290-24-9Relevant academic research and scientific papers
First total synthesis of pyrrolam A
Aoyagi, Yutaka,Manabe, Tomofumi,Ohta, Akihiro,Kurihara, Teruo,Pang, Gui-Lin,Yuhara, Takeo
, p. 869 - 876 (2007/10/03)
First synthesis of pyrrolam A (1), a pyrrolizidine alkaloid from Streptomyces olivaceus, was accomplished. The SmI2-mediated intramolecular coupling reaction between a bromoalkyl and ynamide group gave solely a cyclized product, which was converted to pyrrolam A (1) efficiently.
