173317-31-2

Upstream product

• 40400-13-3 2-Iodobenzyl bromide 
• 113660-57-4 ethyl (E)-3-(1,2-dimethyl-1H-indol-3-yl)acrylate 
• 38292-40-9 1,2-dimethyl-1H-indole-3-carbaldehyde 
• 4622-38-2 2-iodobenzyliodide 

Relevant academic research and scientific papers

Intramolecular Heck reaction: Synthesis of potential antiinflammatory agents

An intramolecular Heck reaction is performed with palladium acetate on iodoethylenic ester 9b to afford in good yield the tetracyclic ester 6 which gave access to potential antiinflammatory agents.

Intramolecular heck reaction: Synthesis of benzo[4,5]cyclohepta[b]indole derivatives

An intramolecular Heck reaction was performed with palladium(II) acetate on iodoethylenic esters 6-7 to afford an ethylenic seven-membered system 8- 9. α-alkylation of 8 was investigated to afford the corresponding α-methyl compound 10. This new family of compounds 11-12 gave access to potential antiinflammatory agents.